储存温度
2-8°C
SMILES字符串
Cl[H].Cl[H].Cn1cnc(CCN)c1
InChI
1S/C6H11N3.2ClH/c1-9-4-6(2-3-7)8-5-9;;/h4-5H,2-3,7H2,1H3;2*1H
InChI key
AGXVEALMQHTMSW-UHFFFAOYSA-N
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生化/生理作用
通过组胺N-甲基转移酶产生的组胺的主要代谢产物。
其他说明
Similar to M 4910, but prepared for Sigma.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
Mikaël Croyal et al.
Analytical biochemistry, 409(1), 28-36 (2010-10-12)
An ultra-performance liquid chromatography tandem mass spectrometry (UPLC™-MS/MS) assay was developed for the simultaneous analysis of histamine, its major metabolite tele-methylhistamine, and an internal standard (N-tele-(R)-α-dimethylhistamine) from human cerebrospinal fluid (CSF) samples. The method involves derivatization of primary amines with
Peter C Konturek et al.
Medical science monitor : international medical journal of experimental and clinical research, 14(9), CR452-CR458 (2008-09-02)
There is some evidence that Helicobacter pylori (Hp) infection may protect against asthma and allergy. The aim of the present study was to analyse the prevalence of Hp infection in adults with proven food allergy and to compare it with
Seiichi Chiba et al.
Brain research bulletin, 79(1), 37-40 (2009-01-20)
Histamine suppresses feeding behavior via histamine H1 receptors in the hypothalamus. This study was performed to examine whether the acute reduction of histamine release in the hypothalamus caused by immepip, a histamine H3 agonist, modulates the feeding behavior of rats.
Brain histamine turnover and seizure behaviour in two mouse strains: preliminary findings.
L Tuomisto et al.
Inflammation research : official journal of the European Histamine Research Society ... [et al.], 52 Suppl 1, S27-S28 (2003-05-21)
M Motawaj et al.
The Journal of pharmacology and experimental therapeutics, 336(2), 479-487 (2010-11-09)
We previously reported that some N-methyl-D-aspartate (NMDA)-receptor antagonists enhanced histamine neuron activity in rodents. Here, we have investigated the effects of memantine, an NMDA-receptor antagonist used for the treatment of Alzheimer's disease, on histaminergic neurotransmission. In vitro, memantine antagonized native
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