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Merck
CN

M4545

Sigma-Aldrich

L-Methionine γ-lyase from Pseudomonas putida

lyophilized powder, pkg of ≥1.0 units/vial

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表单

lyophilized powder

包装

pkg of ≥1.0 units/vial

储存温度

−20°C

其他说明

One unit will release 1.0 μmol of α-ketobutyrate from L-methionine per min at pH 8.0 at 37 °C.

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

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Gil M Penuliar et al.
The Journal of antimicrobial chemotherapy, 66(9), 2045-2052 (2011-06-17)
To determine the mechanism of trifluoromethionine resistance in Entamoeba histolytica and evaluate the impact of acquired drug resistance on virulence. Trifluoromethionine-resistant amoebae were selected in vitro and examined for cross-resistance to antiamoebic drugs, stability of resistance, methionine γ-lyase (MGL) activity
Kyosuke Suwabe et al.
Microbiology (Reading, England), 157(Pt 10), 2992-3000 (2011-07-30)
Fusobacterium nucleatum produces an abundance of hydrogen sulfide (H(2)S) in the oral cavity that is mediated by several enzymes. The identification and characterization of three distinct enzymes (Fn0625, Fn1055 and Fn1220) in F. nucleatum that catalyse the production of H(2)S
Tanaka, H., et al.
Journal of Applied Biochemistry, 2, 439-439 (1980)
Ignace A Moya et al.
The Biochemical journal, 438(3), 513-521 (2011-06-11)
TFM (L-trifluoromethionine), a potential prodrug, was reported to be toxic towards human pathogens that express MGL (L-methionine γ-lyase; EC 4.4.1.11), a pyridoxal phosphate-containing enzyme that converts L-methionine into α-oxobutyrate, ammonia and methyl mercaptan. It has been hypothesized that the extremely
[Perspectives of developing enzyme-based antitumor drugs].
V S Pokrovskiĭ et al.
Voprosy onkologii, 57(2), 155-164 (2011-08-04)

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