M4632
2-氯-5,5-二甲基-1,3-环己二酮
别名:
2-Chlorodimedone
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关于此项目
经验公式（希尔记法）:
C8H11ClO2
化学文摘社编号:
分子量:
174.62
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
Beilstein/REAXYS Number:
2326749
SMILES string
CC1(C)CC(=O)C(Cl)C(=O)C1
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
mp
161-164 °C (lit.)
format
neat
storage temp.
−20°C
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General description
Substrate for chloroperoxidase.
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
P Barnett et al.
The Journal of biological chemistry, 273(36), 23381-23387 (1998-08-29)
Here we describe the isolation, purification, and basic kinetic parameters of a vanadium type chloroperoxidase from the hyphomycete fungus Embellisia didymospora. The enzyme proved to possess similar high substrate affinities, a Km of 5 microM for a bromide, 1.2 mM
Tina Kirchner et al.
Archives of biochemistry and biophysics, 495(1), 21-27 (2009-12-19)
The heme-containing enzyme myeloperoxidase (MPO) accumulates at inflammatory sites and is able to catalyse one- and two-electron oxidation reactions. Here it is shown that (-)-epicatechin, which is known to have numerous beneficial health effects, in low micromolar concentration enhances the
K W Zuurbier et al.
Biochimica et biophysica acta, 1037(2), 140-146 (1990-02-09)
The steady-state activity of myeloperoxidase in the chlorination of monochlorodimedone at neutral pH was investigated. Using a stopped-flow spectrophotometer we were able to show that the enzymic activity at pH 7.2 rapidly declined in time. During the first 50-100 ms
E de Boer et al.
The Journal of biological chemistry, 263(25), 12326-12332 (1988-09-05)
The reaction of vanadium-bromoperoxidase from the brown alga Ascophyllum nodosum with hydrogen peroxide, bromide, and 2-chlorodimedone has been subjected to an extensive steady-state kinetic analysis. Systematic variation of pH and the concentrations of these three components demonstrate that the reaction
D Nowak et al.
Free radical biology & medicine, 16(4), 517-522 (1994-04-01)
We tested whether Ambroxol, a drug which stimulates the release of surfactant by pneumocytes type II, may also possess antioxidant properties. To assess the reactivity of Ambroxol with reactive oxygen species, we analysed its ability to decompose hydrogen peroxide (H2O2)
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