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Merck
CN

M6014

Met-Leu-Phe acetate salt

≥97% (HPLC)

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关于此项目

经验公式(希尔记法):
C20H31N3O4S
化学文摘社编号:
分子量:
409.54
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
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assay

≥97% (HPLC)

storage temp.

−20°C

SMILES string

CSCCC(N)C(=O)NC(CC(C)C)C(=O)NC(Cc1ccccc1)C(O)=O

InChI

1S/C20H31N3O4S/c1-13(2)11-16(22-18(24)15(21)9-10-28-3)19(25)23-17(20(26)27)12-14-7-5-4-6-8-14/h4-8,13,15-17H,9-12,21H2,1-3H3,(H,22,24)(H,23,25)(H,26,27)

InChI key

CHDYFPCQVUOJEB-UHFFFAOYSA-N

Analysis Note

Exhibits very weak chemotactic properties.


存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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Didier G Ebo et al.
Journal of immunological methods, 375(1-2), 30-38 (2011-09-29)
Stimulated human basophils exhibit different degranulation patterns with release of mediators and appearance of activation markers such as CD63 and CD203c. Traditionally, released mediators are quantified in the supernatant of activated cells, whereas the expression of activation markers by individual
E S Buescher et al.
Cancer immunology, immunotherapy : CII, 37(1), 26-30 (1993-07-01)
During a phase I trial of interleukin-1 alpha (IL-1 alpha) in patients with ovarian carcinomas, the effects of this treatment on blood granulocyte respiratory burst and locomotive responses were examined. Differences in baseline granulocyte function in patients as well as
W Tao et al.
The Biochemical journal, 257(3), 633-637 (1989-02-01)
[3H]Arachidonic acid is released after stimulation of rabbit neutrophils with fMet-Leu-Phe or platelet-activating factor (PAF). The release is rapid and dose-dependent, and is inhibited in phorbol 12-myristate 13-acetate (PMA)-treated rabbit neutrophils. The protein kinase C (PKC) inhibitor 1-(5-isoquinoline-sulphonyl)-2-methylpiperazine (H-7) prevents