M6390
份菁 540
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关于此项目
经验公式（希尔记法）:
C26H32N3NaO6S2
化学文摘社编号:
分子量:
569.67
UNSPSC Code:
41116107
Beilstein/REAXYS Number:
3585252
MDL number:
InChI key
OSQUFVVXNRMSHL-LTHRDKTGSA-M
SMILES string
[Na+].CCCCN1C(=O)C(=C\C=C\C=C2/Oc3ccccc3N2CCCS([O-])(=O)=O)\C(=O)N(CCCC)C1=S
InChI
1S/C26H33N3O6S2.Na/c1-3-5-16-28-24(30)20(25(31)29(26(28)36)17-6-4-2)12-7-10-15-23-27(18-11-19-37(32,33)34)21-13-8-9-14-22(21)35-23;/h7-10,12-15H,3-6,11,16-19H2,1-2H3,(H,32,33,34);/q;+1/p-1/b10-7+,23-15-;
mp
285 °C (dec.) (lit.)
storage temp.
2-8°C
Application
Impermeant fluorescent probe for membrane potential and permeability, photoxidation of the membrane-bound dye differentially modifies membrane permeability.
法规信息
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R C Meagher et al.
Journal of cellular physiology, 116(1), 118-124 (1983-07-01)
Merocyanine 540 (MC 540) is an impermeant fluorescent dye that binds preferentially to fluidlike domains of the cell membrane. Photoexcitation of membrane-bound dye causes a breakdown of the normal permeability properties of the membrane and, eventually, cell death. We have
K W Kinnally et al.
Biochemistry, 17(16), 3419-3428 (1978-08-08)
A number of cationic or anionic fluorescent dyes were investigated as possible monitors of the membrane potential of rat liver mitochondria, and giant mitochondria isolated from the liver of mice maintained on a diet containing cuprizone. The fluorescence of four
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