Monoclonal Anti-MRP3 antibody produced in mouse

Multidrug Resistance-Associated Protein (MRP) is a seven member subfamily of ABC (ATP-binding cassette) transporters. MRP1, 2, and 3 have a similar structure with the ability to transport glutathione and glucuronate conjugates. MRP4 and MRP5 share more structure similarity with each other than with MRP1, 2, and 3. MRP4 and MRP5 also have the ability to transport cyclic nucleotides..The monoclonal anti-MRP3 recognizes human Multidrug Resistance-Associated Protein 3 (MRP3, 190-200 kDA)..

fusion protein of MRP3 (amino acids 830-949).

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)

The antibody may be used in immunocytochemistry, immunoblotting, immunohistochemistry.

Reacts with an internal epitope of MRP3. Does not cross-react with the human MDR1, MRP1, MRP2, or MRP5 gene products.

Supplied in serum-free medium containing 0.7% bovine serum albumin and 0.1% sodium azide.

Monoclonal Anti-Multidrug Resistance-Associated Protein 3 (MRP3), mouse isotype IgG1, derived using M₃II-21 hybridoma produced by fusion SP2/O mouse myeloma cells and Balb/c mouse lymph nodes cells immunized with amino acids 830-949 of the human MRP3 bacterial fusion protein. The antibody is concentrated from culture supernatant of M₃II-21 hybridoma cells grown in a bioreactor.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.