biological source
mouse
conjugate
unconjugated
antibody form
tissue culture supernatant
antibody product type
primary antibodies
clone
p193-6, monoclonal
species reactivity
human
concentration
250 μg/mL
technique(s)
immunocytochemistry: 1:10-1:20 using 4% paraformaldehyde-fixed cytospin preparations, immunohistochemistry (frozen sections): 1:10-1:20, western blot (chemiluminescent): 1:10-1:20
isotype
IgG2bκ
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
Quality Level
Gene Information
human ... PARP4(143)
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General description
Minor vault protein 193 is also known as poly (ADP-ribose) polymerase family member 4 (PARP4). Along with two other proteins, it is part of vaults (ribonucleoprotein particles present in the cytoplasm). The molecular weight of this protein is 193kDa.
Immunogen
E. coli lysate transformed with the pET28a(+) expression vector containing amino acids 408-611 of the p193 cDNA.
Biochem/physiol Actions
Minor vault protein 193 is highly expressed in tumors.
Reacts with an internal epitope (aa 593-599, FSKVEDY) of p193.
Physical form
Supplied in serum-free culture medium containing 0.7% bovine serum albulin and 0.1% sodium azide.
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存储类别
10 - Combustible liquids
法规信息
新产品
此项目有
Expression profiles of vault components MVP, TEP1 and vPARP and their correlation to other multidrug resistance proteins in ovarian cancer.
Szaflarski W
International Journal of Oncology, 43(2), 513-520 (2013)
The 193-kD vault protein, VPARP, is a novel poly(ADP-ribose) polymerase.
Kickhoefer VA
The Journal of Cell Biology, 146(5), 917-928 (1999)
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