M7320
N-methylhistaprodifen 二草酸盐
≥98% (HPLC), solid
别名:
N-Methyl-2-[2-(3,3-diphenylpropyl)-1H-imidazol -4-yl]-ethanamine 二草酸盐
方案
≥98% (HPLC)
表单
solid
颜色
white
溶解性
DMSO: ≥10 mg/mL
H2O: insoluble <2 mg/mL
储存温度
2-8°C
SMILES字符串
OC(=O)C(O)=O.OC(=O)C(O)=O.CNCCc1c[nH]c(CCC(c2ccccc2)c3ccccc3)n1
生化/生理作用
N-Methylhistaprodifen is a H1 histamine receptor agonist.
N-Methylhistaprodifen is more potent than histamine by a factor of 3.5 on guinea pig ileum; more potent than histamine by a factor of 4.3 on guinea pig arterial H1-receptor-mediated vasoconstriction; most potent H1-receptor agonist on the guinea pig ileum out of 17 agonists tested. pEC50 = 7.24 in contraction of guinea pig ileal whole segments; pEC50 = 6.31 in contraction of guinea pig aortic segments. N-methylhistaprodifen does not stimulate H2 and H3 histamine receptors; potential use in the study of H1-receptor-mediated physiological and pathophysiological functions.
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持