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Merck
CN

M8759

3-马来酰亚胺基苯甲酸 N -羟基琥珀酰亚胺酯

别名:

MBS

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关于此项目

经验公式(希尔记法):
C15H10N2O6
化学文摘社编号:
分子量:
314.25
EC Number:
261-368-8
UNSPSC Code:
47101511
PubChem Substance ID:
Beilstein/REAXYS Number:
1505254
MDL number:
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mp

175-177 °C (lit.)

solubility

ethyl acetate or DMF: ≤20 mg/mL (may require addition of solvent to coupling buffer to at least 5% to maintain solubility)

storage temp.

−20°C

SMILES string

O=C1CCC(N1OC(C2=CC=CC(N3C(C=CC3=O)=O)=C2)=O)=O

InChI

1S/C15H10N2O6/c18-11-4-5-12(19)16(11)10-3-1-2-9(8-10)15(22)23-17-13(20)6-7-14(17)21/h1-5,8H,6-7H2

InChI key

LLXVXPPXELIDGQ-UHFFFAOYSA-N

Application

对伯胺和巯基具有反应性的双异官能化交联剂。通常,初始反应在 pH 为 7.0 时,通过酰胺键偶联至含伯胺的分子,然后在相同 pH 通过硫醚偶联至含巯基的化合物。用于制备酶免疫交联剂和半抗原载体分子偶联物。

Other Notes

芳基马来酰亚胺比烷基马来酰亚胺连接基更不稳定。


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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Tatsuya Maruhashi et al.
Hypertension research : official journal of the Japanese Society of Hypertension, 38(7), 485-490 (2015-03-06)
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N Sattayasai et al.
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