M9426
MAP Kinase, N-terminal histidine-tagged non-activated protein from rat
≥95% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, 500 U/mg (Can be activated by MEK to more than 500 units per mg)
别名:
ERK2, Extracellular-signal regulated kinase, MAPK, Mitogen activated protein kinase
生物来源
rat
质量水平
重组
expressed in E. coli
方案
≥95% (SDS-PAGE)
表单
lyophilized powder
比活
500 U/mg (Can be activated by MEK to more than 500 units per mg)
分子量
42 kDa
UniProt登记号
应用
cell analysis
储存温度
−20°C
基因信息
rat ... Mapk1(116590)
生化/生理作用
MAP kinase is a serine/threonine kinase that is activated by MEK through a phosphorylation cascade. The cascade starts with extracellular signals transmitted by growth factor-regulated receptor tyrosine kinases or G-protein coupled receptors. Dually phosphorylated (Thr and Tyr) MAP kinase translocates from the cytoplasm to the nucleus, where it phosphorylates protein transcription factors, transducing extracellular signals into genomic responses, proliferation or differentiation.
外形
Lyophilized powder containing Tris, pH 7.5, NaCl, and EGTA, with DTT and trehalose as stabilizers
其他说明
One unit of activated MAP kinase will transfer 1 nmol of phosphate from ATP to myelin basic protein per min at 30 °C.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
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相关内容
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