InChI
1S/C30H41N7O6/c1-19(2)25(27(40)34-22(18-38)16-20-10-5-3-6-11-20)37-26(39)23(14-9-15-33-29(31)32)35-30(43)36-24(28(41)42)17-21-12-7-4-8-13-21/h3-8,10-13,18-19,22-25H,9,14-17H2,1-2H3,(H,34,40)(H,37,39)(H,41,42)(H4,31,32,33)(H2,35,36,43)/t22-,23-,24-,25-/m0/s1
SMILES string
[H]C(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)N[C@@H](Cc2ccccc2)C(O)=O)C(C)C
InChI key
SABSBIPNNYDZRS-QORCZRPOSA-N
assay
≥95%
form
solid
shipped in
dry ice
storage temp.
−20°C
Application
Microbial alkaline protease inhibitor that binds strongly to the active site of the HIV protease.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Structural elucidation of α-MAPI, a novel microbial alkaline proteinase inhibitor, produced by Streptomyces nigrescens.
T. Watanabe, et al.
THL, 7, 625-625 (1979)
E Sarubbi et al.
FEBS letters, 279(2), 265-269 (1991-02-25)
A novel method for discovery of HIV-1 protease inhibitors in complex biological samples has been developed. The assay is based on two specific reagents: a recombinant protein constituted by a portion of the HIV-1 Gag polyprotein comprising the p17-p24 cleavage
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