usage
sufficient for 100 colorimetric tests
application(s)
cosmetics
food and beverages
detection method
colorimetric
relevant disease(s)
cancer; hematological disorder
storage temp.
−20°C
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General description
铁是一种矿物质，在DNA合成、电子转移和氧运输等许多生物过程中发挥着至关重要的作用。铁是一种过渡元素，可形成一系列氧化态，最常见的是铁II（Fe2+ 或亚铁）和铁III（Fe3+ 或三价铁）。含铁蛋白参与许多反应，通常利用铁的氧化态的瞬时变化进行化学反应。
Application
适用于测定各种样品中的铁浓度。
铁含量检测试剂盒已被用于测定鲍曼不动杆菌（A. baumannii）野生型（WT）和Δ铁吸收调节蛋白（Fur）菌株中Fe2+ 的浓度。
Biochem/physiol Actions
在该测定中，通过添加酸性缓冲液而使样品释放铁。可直接测定样品中的Fe2+ 或将样品还原后测量总铁（Fe2+ 和Fe3+）。释放的铁与发色团反应，得到的比色（593nm）产物与样品中的铁含量成比例。铁含量检测试剂盒提供了一种简单方便的铁含量测定方法，适用于各种生物样品。
Preparation Note
试剂盒与血清和组织样本相容，但与血浆样本不相容。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2
存储类别
8A - Combustible corrosive hazardous materials
Manman Xu et al.
Journal of cellular physiology, 234(4), 4232-4242 (2018-08-23)
Previous studies have demonstrated an effect of estrogen on iron metabolism in peripheral tissues. The role of estrogen on brain iron metabolism is currently unknown. In this study, we investigated the effect and mechanism of estrogen on iron transport proteins.
Ems T, Huecker MR
Biochemistry, Iron Absorption (2018)
Contributions of ferric uptake regulator Fur to the sensitivity and oxidative response of Acinetobacter baumannii to antibiotics
Ajiboye T o, et al.
Microbial Pathogenesis, 119, 35-41 (2018)
Bin Lan et al.
Journal of integrative medicine, 18(4), 344-350 (2020-02-29)
Our previous research showed that Naotaifang (a compound traditional Chinese herbal medicine) extract (NTE) has clinically beneficial effects on neurological improvement of patients with acute cerebral ischemia. In this study, we investigated whether NTE protected acute brain injury in rats
Jing Ye et al.
Theranostics, 10(26), 12072-12089 (2020-11-19)
Background: Among head and neck squamous cell carcinomas (HNSCCs), hypopharyngeal squamous cell carcinoma (HPSCC) has the worst prognosis. Iron metabolism, which plays a crucial role in tumor progression, is mainly regulated by alterations to genes and post-transcriptional processes. The recent
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