产品名称
NAD/NADH 定量试剂盒, sufficient for 100 colorimetric tests
usage
sufficient for 100 colorimetric tests
detection method
colorimetric
relevant disease(s)
cancer
storage temp.
−20°C
Application
NAD/NADH定量试剂盒已可用于,当存在曲美他嗪时,SIRT1(去乙酰化酶1)活性(与缺血再灌注损伤相关)对NAD+/NADH定量的影响。
适用于动物组织(肝、肾等)、细胞培养(贴壁细胞或悬浮细胞)、血清或尿液中NADH和NAD的检测。
Biochem/physiol Actions
NAD/NADH定量试剂盒为敏感检测细胞内核苷酸、NAD(烟酰胺腺嘌呤二核苷酸)和NADH及它们的比值提供了一种方便的工具,无需从样品中纯化NAD/NADH。该试剂盒针对NAD和NADH,不检测NADP或NADPH。NADt(NAD和NADH)或NADH在比色法(450 nm)中定量。
General description
烟酰胺腺嘌呤二核苷酸(NAD)是一种参与多种氧化还原反应的酶辅因子。NAD作为电子载体,在氧化(NAD)和还原(NADH)形式之间循环。NAD除了在氧化还原反应中发挥作用外,在ADP(二磷酸腺苷)-核糖基化反应和作为去乙酰化酶的底物中也发挥着关键作用。
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Warning
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Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
存储类别
10 - Combustible liquids
法规信息
常规特殊物品
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本页面介绍了一篇有关瓦博格效应的文章,以及其如何能够在正常氧气水平下,增强肿瘤细胞中葡萄糖向乳酸的转化。Otto Heinrich Warburg在1924年证明,癌细胞显示出对糖酵解的依赖性增加,以满足他们的能量需求,无论是否有充足的氧气存在。
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