application(s)
pharmaceutical
detection method
colorimetric, fluorometric
relevant disease(s)
gastrointestinal diseases
storage temp.
−20°C
General description
肝脂肪变性，又称为脂肪肝，是一种以肝脏内脂肪滴过度积累为特征的疾病。这可能由多种因素引起，包括饮酒过量、肥胖和其他脂肪代谢异常疾病。肝脂肪变性常被用作确定候选药物肝毒性的指标。
Application
Evaluate hepatic steatosis, quantify triglycerides, and visualize lipid droplet accumulation in hepatocytes. As well as screen drug candidates for steatotic risk.
Biochem/physiol Actions
The Hepatic Steatosis Kit detects triglyceride accumulation and lipid droplet formation in hepatocytes. The kit can be used to screen and evaluate steatosis risk of drug candidates and to study the mechanism of steatosis development. Chloroquine is included as a positive control for inducing steatosis in liver cells, such as HepG2.
signalword
Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Muta. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
target_organs
Respiratory system
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
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