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Merck
CN

N0509

Neurotensin Fragment 1-8

≥97% (HPLC)

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关于此项目

经验公式(希尔记法):
C46H71N13O14
化学文摘社编号:
分子量:
1030.13
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
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assay

≥97% (HPLC)

UniProt accession no.

storage temp.

−20°C

SMILES string

CC(C)CC(NC(=O)C1CCC(=O)N1)C(=O)NC(Cc2ccc(O)cc2)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CCCCN)C(=O)N3CCCC3C(=O)NC(CCCNC(N)=N)C(O)=O

Gene Information

human ... NTS(4922)

Application

Used to identify antibody specificities in cross-reactivity studies.

存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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C F Ferris et al.
Regulatory peptides, 12(2), 101-111 (1985-10-01)
The levels of neurotensin (NT) and its metabolite, the N-terminal octapeptide (NT1-8), identified by HPLC and measured by RIA, were increased in the hepatic-portal circulation of the anesthetized rat during perfusion of the small intestine with a lipid solution, while
R Nustede et al.
Pancreas, 4(1), 114-119 (1989-01-01)
Stimulation of the exocrine pancreas is one of the biological effects attributed to the tridecapeptide neurotensin (NT). Only the C-terminal 8-13 fragment with its extremely short plasma half-life in the peripheral circulation was considered to be necessary for biological activity.
Y F Lu et al.
Brain research bulletin, 40(2), 135-141 (1996-01-01)
The effects of neurotensin (NT) on neurons in the central amygdaloid nucleus (ACe) were investigated in rat brain slice preparations by adding the peptide to the perfusing medium. Of 115 ACe neurons, 69 cells (60%) showed excitatory responses and 10
M F Pozza et al.
European journal of pharmacology, 145(3), 341-343 (1988-01-19)
The electrophysiological effects of neurotensin (NT), its analog xenopsin, and the fragment NT-(1-8) on the activity of dopaminergic neurons in rat substantia nigra slices were compared. Xenopsin and NT produced a concentration-dependent increase in the firing rate. The mean firing
M N Castel et al.
Peptides, 10(1), 95-101 (1989-01-01)
The electroencephalographic (EEG) effects of the ICV administration of neurotensin (NT 1-13), NT 1-8 (an inactive neurotensin fragment) and D TYR-11 NT (a long-lasting analog of neurotensin) were studied in rats. In awake rats, NT 1-13 (30 micrograms) and D

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