Monoclonla Anti-Nup62/p62 大鼠抗

Monoclonal Anti-Nup62/p62 (rat IgG1) is derived from the hybridoma 2A11 produced by the fusion of mouse myeloma cells (SP2 cells) and splenocytes from WKY/NCrj rat immunized with a recombinant fragment of human Nup62, amino acids 1-300.

Nucleoporin-62kDa (Nup62) is a glycosylated nucleoporin present in the central channel of the nuclear pore complex. The gene encoding it is located on human chromosome 19q13.33 and contains three exons.

recombinant fragment of human Nup62 (amino acids 1-300).

Anti-Nup62/p62 antibody, Mouse monoclonal has been used in immunoblotting (~62 kDa). It is also suitable for enzyme linked immunosorbent assay (ELISA) and immunocytochemistry.

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

The C-terminal end contains a coiled-coil structure aiding in protein-protein interactions that may function in the anchorage of the protein to the pore complex.

Nucleoporin-62kDa (Nup62) has been shown to bind to other nucleoporins. It is involved in nuclear transport. The protein′s amino terminal region acts as a docking site for nuclear transport factor 2 (NTF2).

0.01M 磷酸缓冲盐溶液，pH 7.4，含 15mM 叠氮化钠。

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.