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Merck
CN

N1773

[Ser2]-Neuromedin C

≥97% (HPLC)

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关于此项目

经验公式（希尔记法）:
C49H72N16O11S
化学文摘社编号:
136058-54-3
分子量:
1093.26
UNSPSC Code:
12352202
PubChem Substance ID:
24897526
NACRES:
NA.26
MDL number:
MFCD00214338

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产品名称

[Ser2]-Neuromedin C, ≥97% (HPLC)

SMILES string

CSCCC(NC(=O)C(CC(C)C)NC(=O)C(Cc1cnc[nH]1)NC(=O)CNC(=O)C(NC(=O)C(C)NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(Cc4cnc[nH]4)NC(=O)C(CO)NC(=O)CN)C(C)C)C(N)=O

InChI

1S/C49H72N16O11S/c1-25(2)13-34(45(72)61-33(42(51)69)11-12-77-6)62-46(73)36(15-29-19-52-23-56-29)59-40(68)21-55-49(76)41(26(3)4)65-43(70)27(5)58-44(71)35(14-28-18-54-32-10-8-7-9-31(28)32)63-47(74)37(16-30-20-53-24-57-30)64-48(75)38(22-66)60-39(67)17-50/h7-10,18-20,23-27,33-38,41,54,66H,11-17,21-22,50H2,1-6H3,(H2,51,69)(H,52,56)(H,53,57)(H,55,76)(H,58,71)(H,59,68)(H,60,67)(H,61,72)(H,62,73)(H,63,74)(H,64,75)(H,65,70)

InChI key

CDSKUMVQOSVSRF-UHFFFAOYSA-N

assay

≥97% (HPLC)

form

solid

composition

Peptide content, ~70%

UniProt accession no.

P07492

storage temp.

−20°C

Quality Level

200

Gene Information

human ... GRP(2922)

Biochem/physiol Actions

[Ser2]-Neuromedin C is a bombesin-like peptide known to inhibit feeding.

Other Notes

Bombesin-like peptide originally isolated from the brain of the European green frog, Rana ridibunda.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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Eva Mónika Fekete et al.
Brain research bulletin, 71(4), 386-392 (2007-01-09)
Bombesin-like peptides including gastrin releasing peptide and neuromedin C are known to inhibit feeding. Bombesin receptors have been found in moderate to high densities in the amygdaloid body, which is essentially involved in the regulation of feeding and body weight.
Biochemical and Biophysical Research Communications, 178, 529-529 (1991)

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