生物来源
human
重组
expressed in E. coli
方案
>97% (SDS-PAGE)
表单
lyophilized powder
效能
0.1-0.3 μg/mL ED50 (cytochalasin B treated human neutrophils)
0.1-0.5 ng/mL ED50 (BaF/3 hCXCR-2 transfected cells)
分子量
~7.6 kDa
储存条件
avoid repeated freeze/thaw cycles (Storage in "frost-free" freezers is not recommended)
技术
cell culture | mammalian: suitable
杂质
endotoxin, tested
UniProt登记号
储存温度
−20°C
基因信息
human ... PPBP(5473)
生化/生理作用
Neutrophil Activating Peptide-2, a member of the CXC chemokine family, chemoattracts and activates neutrophils and also binds CXCR-2. NAP-2 is proteolytically processed C-terminal fragments of platelet basic protein (PBP), which is found in the α-granules of human platelets.
外形
Lyophilized from a 0.2 μm filtered solution in 30% acetonitrile and 0.1% trifluoroacetic acid containing 0.5 mg bovine serum albumin.
分析说明
The biological activity is measured by the induction of myeloperoxidase release from cytochalasin B treated human neutrophils.
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