N2268
Nω-硝基-L-精氨酸对硝基苯胺 氢溴酸盐
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关于此项目
经验公式(希尔记法):
C12H17N7O5 · HBr
化学文摘社编号:
分子量:
420.22
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.26
杂质
≤20% dioxane as solvent of crystallization
储存温度
−20°C
SMILES字符串
Br.N[C@@H](CCCNC(=N)N[N+]([O-])=O)C(=O)Nc1ccc(cc1)[N+]([O-])=O
InChI
1S/C12H17N7O5.BrH/c13-10(2-1-7-15-12(14)17-19(23)24)11(20)16-8-3-5-9(6-4-8)18(21)22;/h3-6,10H,1-2,7,13H2,(H,16,20)(H3,14,15,17);1H/t10-;/m0./s1
InChI key
VLIUCLVWDVXVTH-PPHPATTJSA-N
生化/生理作用
Nω-Nitro-L-arginine p-nitroanilide hydrobromide inhibits neuronal NO synthase.
警示用语:
Danger
危险分类
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
新产品
此项目有
S Burlet et al.
Neuroscience letters, 226(2), 131-135 (1997-04-25)
A sensor allowing the specific detection of nitric oxide (NO) is reported. Together with differential pulsed voltammetry, it allows the detection of a 650 mV signal either in NO solutions or in the rat frontal cortex. The intraperitoneal (i.p.) administration
B Hars
Brain research, 816(1), 209-219 (1999-01-08)
Pontine cholinergic structures are known to play a key role in the regulation of vigilance states associated with desynchronised EEG, i. e., wakefulness and paradoxical sleep. As the cholinergic cells of these nuclei, the pedunculopontine tegmentum (PPT) and the laterodorsal
Seyed-Hossein Riazimand et al.
BJU international, 96(6), 900-908 (2005-09-13)
To investigate to what extent antagonists of spinal neurotransmitters interact with the effects of sacral neuromodulation in a rat model of a chronically hyperactive urinary bladder. In female rats the urinary bladder was instilled with turpentine oil 2.5% to induce
J B Su et al.
Circulation, 101(15), 1848-1853 (2000-04-19)
Constitutive bradykinin B(1) receptors have been identified in dogs; however, their physiological implications involving the coronary circulation remain to be determined. This study examined, in conscious dogs, the coronary response to des-Arg(9)-bradykinin (a B(1) receptor agonist) and the mechanisms involved.
F Lhuillier et al.
British journal of anaesthesia, 97(2), 137-146 (2006-04-15)
Direct evidence of nitric oxide (NO) involvement in the regulation of hepatic microcirculation is not yet available under physiological conditions nor in haemorrhagic shock. A laser Doppler flowmetry was used to measure liver perfusion index and a specific NO-sensitive electrode
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