N2268
Nω-硝基-L-精氨酸对硝基苯胺 氢溴酸盐
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关于此项目
经验公式（希尔记法）:
C12H17N7O5 · HBr
化学文摘社编号:
分子量:
420.22
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
InChI
1S/C12H17N7O5.BrH/c13-10(2-1-7-15-12(14)17-19(23)24)11(20)16-8-3-5-9(6-4-8)18(21)22;/h3-6,10H,1-2,7,13H2,(H,16,20)(H3,14,15,17);1H/t10-;/m0./s1
SMILES string
Br.N[C@@H](CCCNC(=N)N[N+]([O-])=O)C(=O)Nc1ccc(cc1)[N+]([O-])=O
InChI key
VLIUCLVWDVXVTH-PPHPATTJSA-N
impurities
≤20% dioxane as solvent of crystallization
storage temp.
−20°C
Biochem/physiol Actions
Nω-Nitro-L-arginine p-nitroanilide hydrobromide inhibits neuronal NO synthase.
signalword
Danger
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
新产品
此项目有
Seyed-Hossein Riazimand et al.
BJU international, 96(6), 900-908 (2005-09-13)
To investigate to what extent antagonists of spinal neurotransmitters interact with the effects of sacral neuromodulation in a rat model of a chronically hyperactive urinary bladder. In female rats the urinary bladder was instilled with turpentine oil 2.5% to induce
S Burlet et al.
Neuroscience letters, 226(2), 131-135 (1997-04-25)
A sensor allowing the specific detection of nitric oxide (NO) is reported. Together with differential pulsed voltammetry, it allows the detection of a 650 mV signal either in NO solutions or in the rat frontal cortex. The intraperitoneal (i.p.) administration
B Hars
Brain research, 816(1), 209-219 (1999-01-08)
Pontine cholinergic structures are known to play a key role in the regulation of vigilance states associated with desynchronised EEG, i. e., wakefulness and paradoxical sleep. As the cholinergic cells of these nuclei, the pedunculopontine tegmentum (PPT) and the laterodorsal
The role of nitric oxide in inhibitory neurotransmission in the middle cerebral artery of the sheep.
J D Matthew et al.
General pharmacology, 28(3), 393-397 (1997-03-01)
1. The involvement of nitric oxide (NO) as a mediator of inhibitory neurotransmission and its potential release mechanism in sheep isolated middle cerebral artery rings was investigated using NO synthase inhibitors, haemolysate, superoxide dismutase (SOD) and omega-conotoxin GVIA. In the
M B Vroom et al.
British journal of anaesthesia, 76(1), 122-129 (1996-01-01)
In the present study, we investigated if the relaxant effects of phosphodiesterase (PDE) III inhibitors on human vessels could be inhibited by a nitric oxide synthase blocker, L-NAME, or by a blocker of ATP-sensitive potassium channels (KATP), glibenclamide. The experiments
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