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Merck
CN

N3395

Nomilin

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经验公式(希尔记法):
C28H34O9
化学文摘社编号:
分子量:
514.56
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
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SMILES string

CC(=O)OC1CC(=O)OC(C)(C)[C@@H]2CC(=O)[C@]3(C)[C@H](CC[C@@]4(C)[C@@H](OC(=O)[C@H]5O[C@@]345)c6ccoc6)[C@@]12C

InChI

1S/C28H34O9/c1-14(29)34-19-12-20(31)36-24(2,3)17-11-18(30)27(6)16(26(17,19)5)7-9-25(4)21(15-8-10-33-13-15)35-23(32)22-28(25,27)37-22/h8,10,13,16-17,19,21-22H,7,9,11-12H2,1-6H3/t16-,17+,19?,21+,22-,25+,26-,27+,28-/m1/s1

InChI key

KPDOJFFZKAUIOE-BIYZDVJRSA-N

Biochem/physiol Actions

Has anti-proliferative activity on cultured human breast cancer cells.


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存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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分析证书(COA)

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Emanuela Balestrieri et al.
Bioorganic & medicinal chemistry, 19(6), 2084-2089 (2011-02-22)
The effects of an extract from Citrus bergamia (BSext) and those of two products purified from the same extract, that is, nomilin and limonin, and reference compounds, towards HTLV-1 have been reported. Moreover, they were also compared with those obtained
E G Miller et al.
Carcinogenesis, 10(8), 1535-1537 (1989-08-01)
Two citrus limonoids, limonin and nomilin, were tested for their effects on the development of 7,12-dimethylbenz[a]anthracene (DMBA)-induced buccal pouch epidermoid carcinomas. Forty-five female Syrian hamsters were divided into three equal groups. The left buccal pouches of the animals in each
Q Tian et al.
Nutrition and cancer, 40(2), 180-184 (2002-04-19)
Limonoids have been shown to inhibit the growth of estrogen receptor-negative and -positive human breast cancer cells in culture. The primary objective of this study was to test the antiproliferative activity of limonoids (obacunone 17 beta-D-glucopyranoside, nomilinic acid 17 beta-D-glucopyranoside