species reactivity
rat
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
96009, monoclonal
form
lyophilized powder
technique(s)
indirect ELISA: 0.5-1 μg/mL using rrNeuropilin-2 extracellular domain, western blot: 1-2 μg/mL using rrNeuropilin-2 extracellular domain
isotype
IgG2b
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
rat ... Nrp2(81527)
General description
Neuropilin-2 (NRP-2) is expressed in the neurons of the developing nervous system in rats.
Immunogen
purified, NS0-derived, recombinant rat neuropilin-2 extracellular domain.
Biochem/physiol Actions
Neuropilin-2 (NRP-2) is involved in assembly of Schwann cells into aggregates, which have a role in the regeneration of neurons.
Shows no cross-reactivity with human neuropilin-1.
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
J Ara et al.
Journal of neuroscience research, 79(4), 468-475 (2005-01-07)
Neuropilins and group A plexins are components of receptor complexes for class 3 semaphorins, gradients of which help to guide migration of neural progenitor cells and axonal growth cones during development. We demonstrated previously that neuropilins and class 3 semaphorins
A L Kolodkin et al.
Cell, 90(4), 753-762 (1997-08-22)
The semaphorin family contains a large number of phylogenetically conserved proteins and includes several members that have been shown to function in repulsive axon guidance. Semaphorin III (Sema III) is a secreted protein that in vitro causes neuronal growth cone
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