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Merck
CN

N3785

Nabilone

solid, ≥98% (HPLC)

别名:

LY-109514

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关于此项目

经验公式（希尔记法）:
C24H36O3
化学文摘社编号:
51022-71-0
分子量:
372.54
NACRES:
NA.77
PubChem Substance ID:
329818640
UNSPSC Code:
12352200
MDL number:
MFCD00941490

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InChI key

GECBBEABIDMGGL-RTBURBONSA-N

SMILES string

CCCCCCC(C)(C)c1cc(O)c2[C@@H]3CC(=O)CC[C@H]3C(C)(C)Oc2c1

InChI

1S/C24H36O3/c1-6-7-8-9-12-23(2,3)16-13-20(26)22-18-15-17(25)10-11-19(18)24(4,5)27-21(22)14-16/h13-14,18-19,26H,6-12,15H2,1-5H3/t18-,19-/m1/s1

assay

≥98% (HPLC)

form

solid

drug control

USDEA Schedule II; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada, kontrollierte Droge in Deutschland

Quality Level

100

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

color

white

solubility

DMSO: soluble ~18 mg/mL, H2O: insoluble

application(s)

forensics and toxicology
veterinary

shipped in

wet ice

storage temp.

2-8°C

相关类别

Biochem/physiol Actions

CB1 and CB2 cannabinoid receptor agonist.

Features and Benefits

This compound is featured on the Cannabinoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Legal Information

German
Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG.

English
This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies.

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Repr. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000082248
071M4604V
087K4623
063K4619

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Regulation of synthetic cannabinoids.
C Heather Ashton et al.
Lancet (London, England), 374(9701), 1595-1595 (2009-11-10)
Mark A Ware et al.
Anesthesia and analgesia, 110(2), 604-610 (2009-12-17)
Sleep disorders affect many patients with chronic pain conditions. Cannabis has been reported by several patient populations to help sleep. We evaluated the safety and efficacy of nabilone, a synthetic cannabinoid, on sleep disturbance in fibromyalgia (FM), a disease characterized
Luigi Alberto Pini et al.
The journal of headache and pain, 13(8), 677-684 (2012-10-17)
Medication overuse headache (MOH) is a severe burden to sufferers and its treatment has few evidence-based indications. The aim of this study is to evaluate efficacy and safety of nabilone in reducing pain and frequency of headache, the number of
Sepideh Pooyania et al.
Archives of physical medicine and rehabilitation, 91(5), 703-707 (2010-05-04)
To determine whether nabilone, a synthetic cannabinoid, alleviates spasticity in people with spinal cord injury (SCI). A double-blind, placebo-controlled crossover study. Outpatient rehabilitation clinics. We recruited volunteers (N=12) with SCI and spasticity. One subject, a paraplegic man, dropped out of
Joshua A Lile et al.
Clinical neuropharmacology, 33(5), 235-242 (2010-09-15)
The central effects of Δ-tetrahydrocannabinol (Δ-THC), the primary active constituent of cannabis, are attributed to cannabinoid CB1 receptor activity, although clinical evidence is limited. Drug discrimination has proven useful for examining the neuropharmacology of drugs, as data are concordant with
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