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Merck
CN

N3912

Monoclonal Anti-Netrin-4 antibody produced in mouse

clone 191633, purified immunoglobulin, lyophilized powder

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
Conjugate:
unconjugated
Clone:
191633, monoclonal
Application:
ELISA (i), WB
Citations:
2
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biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

191633, monoclonal

form

lyophilized powder

species reactivity

human

technique(s)

indirect ELISA: 0.5-1 μg/mL using recombinant human netrin-4, western blot: 1-2 μg/mL using recombinant human netrin-4

isotype

IgG2a

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... NTN4(59277)

General description

Netrin-4 (NTN4) is also called β−netrin and is expressed in the cortex. It is a 628 amino-acid protein.

Immunogen

purified, NS0-derived, recombinant human Netrin-4.

Biochem/physiol Actions

Netrin-4 (NTN4) associates with unc-5 homolog B (Unc5B). It has crucial roles in angiogenesis and axon branching.
This antibody shows no cross-reactivity with rmNetrin-1, rhNetrin-1, rhNetrin-2, or rmNetrin-G1a.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

新产品

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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相关内容

Instructions


Netrin-4 regulates angiogenic responses and tumor cell growth.
Nacht M
Experimental Cell Research, 315(5), 784-794 (2009)
Yasufumi Hayano et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(42), 15226-15231 (2014-10-08)
Axon branching is remodeled by sensory-evoked and spontaneous neuronal activity. However, the underlying molecular mechanism is largely unknown. Here, we demonstrate that the netrin family member netrin-4 (NTN4) contributes to activity-dependent thalamocortical (TC) axon branching. In the postnatal developmental stages



全球贸易项目编号

货号GTIN
N3912-500UG04061833631072