N5020
1-Norokadaone
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关于此项目
经验公式（希尔记法）:
C43H66O11
化学文摘社编号:
分子量:
758.98
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
InChI
1S/C43H66O11/c1-25-21-35(52-43(24-25)36(46)12-11-32(51-43)23-29(5)44)26(2)9-10-31-14-18-42(50-31)19-15-34-40(54-42)37(47)30(6)39(49-34)33(45)22-28(4)38-27(3)13-17-41(53-38)16-7-8-20-48-41/h9-10,24,26-28,31-40,45-47H,6-8,11-23H2,1-5H3/b10-9+
SMILES string
CC1CCC2(CCCCO2)OC1C(C)CC(O)C3OC4CCC5(CCC(O5)\C=C\C(C)C6CC(C)=CC7(OC(CCC7O)CC(C)=O)O6)OC4C(O)C3=C
InChI key
NJOGICJCSWVJKS-MDZDMXLPSA-N
storage temp.
−20°C
Application
May be useful as a negative control.
Other Notes
Okadaic acid analog with low protein phosphatase inhibition and little affinity for receptors.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Skin Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
S Nishiwaki et al.
Carcinogenesis, 11(10), 1837-1841 (1990-10-01)
Okadaic acid (OA) is a potent non-12-O-tetradecanoyl-phorbol-13-acetate (non-TPA) type tumor promoter on mouse skin. OA acts on cells through inhibiting the activity of protein phosphatases and results in the increase of phosphorylation of proteins. Seventeen OA derivatives were evaluated as
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