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Merck
CN

N6162

Anti-Neuropeptide FF1 Receptor (NPFF1) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

别名:

Anti-G protein-coupled Receptor 147 (GPR147), Anti-RFamide-related Peptide Receptor OT7T022

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
2
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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen ~48 kDa

species reactivity

human

technique(s)

western blot: 1:500-1:1,000 using brain lysate

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... NPFFR1(64106)

General description

Neuropeptide FF receptor 1 (NPFF1) is a receptor for the protein RFamide-related peptide-3 (RFRP-3). It is expressed in the ovaries and the gene encoding it is localized on human chromosome 10q21.

Immunogen

peptide corresponding to the C-terminal sequence (amino acids 418-430) and N-terminal sequence (amino acids 1-16) of the NPFF1 protein.

Biochem/physiol Actions

Neuropeptide FF receptor 1 (NPFF1) along with its ligand, prevents gonadotropin signaling.

Physical form

Solution of 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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相关内容


Identification and characterization of two G protein-coupled receptors for neuropeptide FF.
Bonini JA
The Journal of Biological Chemistry, 275(50), 39324-39331 (2000)
Hajime Oishi et al.
Endocrinology, 153(7), 3435-3445 (2012-06-14)
RFamide-related peptide-3 (RFRP-3), a mammalian ortholog of avian gonadotropin-inhibitory hormone, has pronounced inhibitory effects on reproduction in a number of species. RFRP-3 suppresses gonadotropin release at the hypothalamic and/or pituitary levels; however, increasing evidence also suggests putative functions within the



全球贸易项目编号

货号GTIN
N6162-100UG04061833296615