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Merck
CN

N7251

4-硝基邻苯二酚硫酸盐 二钾盐

chromogenic sulphatase substrate, crystalline

别名:

2-羟基-5-硝基苯硫酸盐, 2-羟基-5-硝基苯硫酸盐 二钾盐 一水合物, 硝基儿茶酚硫酸盐 二钾盐

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关于此项目

线性分子式:
C6H3NO7SK2
化学文摘社编号:
分子量:
311.35
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
238-550-0
MDL number:
Beilstein/REAXYS Number:
3805018
Form:
crystalline
Quality level:
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产品名称

4-硝基邻苯二酚硫酸盐 二钾盐, crystalline

form

crystalline

Quality Level

color

yellow

storage temp.

−20°C

SMILES string

[K+].[K+].[O-]c1ccc(cc1OS([O-])(=O)=O)[N+]([O-])=O

InChI

1S/C6H5NO7S.2K/c8-5-2-1-4(7(9)10)3-6(5)14-15(11,12)13;;/h1-3,8H,(H,11,12,13);;/q;2*+1/p-2

InChI key

CKWWBDCAYRJAJB-UHFFFAOYSA-L

General description

4-硝基儿茶酚硫酸盐是一种芳香族硫酸盐。
显色硫酸酯酶底物。

Application

4-硝基儿茶酚硫酸二钾盐被用作粘多糖 VI(MPS VI)分析的底物。它也被用来测量糖胺聚糖(GAG)降解酶-芳基磺化酶B和外糖苷酶的活性。


pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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实验方案

Enzymatic Assay of Sulfatase (EC 3.1.6.1.)

商品

Drug conjugate analysis and the enzymatic hydrolysis of glucuronides


P L Chang et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 32(6), 617-624 (1984-06-01)
A staining reaction was developed to specifically detect arylsulfatase A activity in the presence of arylsulfatases B and C. Nitrocatechol, generated by all arylsulfatases from the substrate p-nitrocatechol sulfate, can be coupled to produce Hatchett 's brown which reacts with
Jin-Peng Sun et al.
The Journal of biological chemistry, 278(35), 33392-33399 (2003-06-18)
The pathogenic bacteria Yersinia are causative agents in human diseases ranging from gastrointestinal syndromes to bubonic plague. There is increasing risk of misuse of infectious agents, such as Yersinia pestis, as weapons of terror as well as instruments of warfare
D B Thompson et al.
Experientia, 42(2), 150-151 (1986-02-15)
Rodent and bovine arylsulfatase B hydrolyze 4-methylumbelliferyl sulfate (4MUS) 10- to 30-fold more efficiently than arylsulfatase A. Therefore, 4MUS grossly underestimates arylsulfatase A activity in the presence of excess arylsulfatase B.



全球贸易项目编号

货号GTIN
N7251-1G04061834117872
N7251-100MG04061832941233
N7251-500MG04061832941240
N7251-5G04061834117889