N8278
N-(NBD-Aminohexanoyl)sphingosine
别名:
N-([7-Nitrobenz-2-oxa-1,3-diazol-4-yl]aminocaproyl)sphingosine, NBD hexanoic ceramide
表单
powder
脂质类型
sphingolipids
储存温度
−20°C
SMILES字符串
CCCCCCCCCCCCC\C=C\[C@@H](O)[C@H](CO)NC(=O)CCCCCNc1ccc(c2nonc12)N(=O)=O
InChI
1S/C30H49N5O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-15-18-27(37)25(23-36)32-28(38)19-16-14-17-22-31-24-20-21-26(35(39)40)30-29(24)33-41-34-30/h15,18,20-21,25,27,31,36-37H,2-14,16-17,19,22-23H2,1H3,(H,32,38)/b18-15+/t25-,27+/m0/s1
InChI key
HZIRBXILQRLFIK-VPZZKNKNSA-N
储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Daniel G Milis et al.
Molecular and cellular biochemistry, 283(1-2), 57-66 (2006-01-31)
The influence of sterol carrier protein-2 (SCP-2) on the cellular metabolism of sphingolipids was examined in control mouse L-cells and stably transfected clones expressing the protein SCP-2. Three approaches were used to examine for differences; (1) compositional analysis of endogenous
K Wolf et al.
Cellular microbiology, 3(3), 145-152 (2001-03-22)
Chlamydia pneumoniae is a bacterial obligate intracellular parasite with a developmental cycle common to all members of the genus Chlamydia. Like other chlamydiae, the developmental cycle of C. pneumoniae occurs entirely within a membrane-bound intracellular vacuole, termed an inclusion, that
Tatsuru Togo
Journal of cell science, 119(Pt 13), 2780-2786 (2006-06-15)
Resealing of a disrupted plasma membrane requires Ca(2+)-regulated exocytosis. Repeated disruptions reseal more quickly than the initial wound. This facilitated response requires both Ca(2+) and protein kinase C (PKC), and is sensitive to brefeldin A. There is also evidence that
Boris Boyanovsky et al.
The Journal of biological chemistry, 278(29), 26992-26999 (2003-05-02)
Ceramide is a bioactive molecule involved in cellular responses to stress and inflammation. The major pathway for ceramide accumulation is via agonist-induced activation of cellular sphingomyelinases. It has also been shown that the ceramide level in circulating low density lipoprotein
E H Pap et al.
Experimental cell research, 265(2), 288-293 (2001-04-17)
Peptides carrying organelle-specific import or retention sequences can target the fluorophore BODIPY(581/591) to the nucleus, peroxisomes, endoplasmic reticulum (ER), or the trans-Golgi network (TGN). The peroxisomal peptide contains the PTS1 sequence AKL. For targeting to the ER or TGN, the
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