N8278
N-(NBD-Aminohexanoyl)sphingosine
别名:
N-([7-Nitrobenz-2-oxa-1,3-diazol-4-yl]aminocaproyl)sphingosine, NBD hexanoic ceramide
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关于此项目
经验公式（希尔记法）:
C30H49N5O6
化学文摘社编号:
分子量:
575.74
UNSPSC Code:
12352211
PubChem Substance ID:
MDL number:
InChI
1S/C30H49N5O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-15-18-27(37)25(23-36)32-28(38)19-16-14-17-22-31-24-20-21-26(35(39)40)30-29(24)33-41-34-30/h15,18,20-21,25,27,31,36-37H,2-14,16-17,19,22-23H2,1H3,(H,32,38)/b18-15+/t25-,27+/m0/s1
SMILES string
CCCCCCCCCCCCC\C=C\[C@@H](O)[C@H](CO)NC(=O)CCCCCNc1ccc(c2nonc12)N(=O)=O
InChI key
HZIRBXILQRLFIK-VPZZKNKNSA-N
form
powder
lipid type
sphingolipids
storage temp.
−20°C
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Asami Makino et al.
Biochemistry, 45(14), 4530-4541 (2006-04-06)
D-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol (D-PDMP) is a frequently used inhibitor of glycosphingolipid biosynthesis. However, some interesting characteristics of D-PDMP cannot be explained by the inhibition of glycolipid synthesis alone. In the present study, we showed that d-PDMP inhibits the activation of lysosomal acid
Olaf Maier et al.
The Journal of biological chemistry, 278(1), 164-173 (2002-10-31)
In HepG2 cells, the subapical compartment (SAC) is involved in the biogenesis of membrane polarity. By contrast, direct apical transport originating from the trans-Golgi network (TGN), which may contribute to polarity establishment, has been poorly defined in these cells. Thus
Diane M Welty et al.
Molecular microbiology, 50(3), 835-843 (2003-11-18)
Although the spirochetal protein OspA is capable of stimulating immune cells in a CD14- and TLR2-dependent manner, little is known about how TLR2 receptor complex ligands, such as OspA, are handled by the cell once delivered. We examine here the
Boris Boyanovsky et al.
The Journal of biological chemistry, 278(29), 26992-26999 (2003-05-02)
Ceramide is a bioactive molecule involved in cellular responses to stress and inflammation. The major pathway for ceramide accumulation is via agonist-induced activation of cellular sphingomyelinases. It has also been shown that the ceramide level in circulating low density lipoprotein
Daniel G Milis et al.
Molecular and cellular biochemistry, 283(1-2), 57-66 (2006-01-31)
The influence of sterol carrier protein-2 (SCP-2) on the cellular metabolism of sphingolipids was examined in control mouse L-cells and stably transfected clones expressing the protein SCP-2. Three approaches were used to examine for differences; (1) compositional analysis of endogenous
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