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Merck
CN

N9627

Nicotinic acid hydroxamate

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关于此项目

经验公式(希尔记法):
C6H6N2O2
化学文摘社编号:
分子量:
138.12
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
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InChI

1S/C6H6N2O2/c9-6(8-10)5-2-1-3-7-4-5/h1-4,10H,(H,8,9)

SMILES string

ONC(=O)c1cccnc1

InChI key

IYCHDNQCHLMLJZ-UHFFFAOYSA-N

form

solid

storage temp.

−20°C

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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K Sugihara et al.
Xenobiotica; the fate of foreign compounds in biological systems, 30(5), 457-467 (2000-06-30)
1. The hydroxamic acids N-hydroxyphenacetin and N-hydroxy-2-acetylaminofluorene were reduced to the corresponding amides, phenacetin and 2-acetylaminofluorene respectively by rabbit blood supplemented with both NAD(P)H and FAD. These reducing activities were found in erythrocytes but not in plasma, and were sensitive
A controlled clinical trial of nicotinohydroxamic acid and neomycin in advanced chronic liver disease.
C Hirayama et al.
Digestion, 25(2), 115-123 (1982-01-01)
R A Izydore et al.
Research communications in chemical pathology and pharmacology, 70(3), 307-321 (1990-12-01)
A series of benzo- and dibenzohydroxamic acids were shown to have potent hypolipidemic activity in mice and rats lowering both serum cholesterol and triglyceride levels at 20 mg/kg/day. Selected derivatives lowered tissue lipids, i.e. liver, small intestine and aorta, and
K Harada et al.
Research communications in chemical pathology and pharmacology, 49(2), 309-312 (1985-08-01)
The effect of oral administrations of nicotinohydroxamic acid (NHA) and neomycin (NM) in ammonia and urea metabolism were investigated in the rat. NHA and NM lowered the blood ammonia level, and NHA increased urinary excretion of urea and depressed urease

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