O0891
Oxymatrine
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关于此项目
经验公式（希尔记法）:
C15H24N2O2
化学文摘社编号:
分子量:
264.36
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.25
方案
≥98% (HPLC)
质量水平
表单
powder
溶解性
methanol: 10 mg/mL, clear, colorless
储存温度
2-8°C
SMILES字符串
[O-][N+]12CCCC3CN4C(CCCC4=O)C(CCC1)C23
InChI
1S/C15H24N2O2/c18-14-7-1-6-13-12-5-3-9-17(19)8-2-4-11(15(12)17)10-16(13)14/h11-13,15H,1-10H2/t11-,12+,13+,15-,17?/m0/s1
InChI key
XVPBINOPNYFXID-LHDUFFHYSA-N
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生化/生理作用
Alkaloid isolated from Sophora flavescens. Antifribotic. Neuroprotective. Traditional chinese medicine used in the treatment against hepatitis B virus.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
监管及禁止进口产品
此项目有
Li Gao et al.
Scientific reports, 8(1), 624-624 (2018-01-14)
Compound Kushen Injection (CKI) is a Traditional Chinese Medicine (TCM) preparation that has been clinically used in China to treat various types of solid tumours. Although several studies have revealed that CKI can inhibit the proliferation of hepatocellular carcinoma (HCC)
Ning-Li Chai et al.
World journal of gastroenterology, 18(31), 4199-4206 (2012-08-25)
To investigate the potential mechanism of Arg-Gly-Asp (RGD) peptide-labeled liposome loading oxymatrine (OM) therapy in CCl₄-induced hepatic fibrosis in rats. We constructed a rat model of CCl₄-induced hepatic fibrosis and treated the rats with different formulations of OM. To evaluate
Ying Zhang et al.
Biochemical pharmacology, 85(1), 59-68 (2012-10-30)
The human ether-a-go-go-related gene (hERG) encodes the rapidly activating, delayed rectifier potassium channel (IKr) important for cardiac repolarization. Dysfunction of the hERG channel can cause Long QT Syndrome (LQTS). A wide variety of structurally diverse therapeutic compounds reduce the hERG
Ruoxi Fan et al.
Fitoterapia, 89, 271-277 (2013-06-12)
A rapid, sensitive and selective high-performance liquid chromatography mass spectrometric method has been developed and validated for the simultaneous determination of oxymatrine and its active metabolite matrine in human plasma after administration of oxymatrine oral solution. Analytes were extracted from
Zhiqiang Wang et al.
International journal of oncology, 49(6), 2331-2340 (2016-10-18)
Lung cancer is the leading cause of cancer-related deaths worldwide and is associated with a very poor outcome. Oxymatrine exerts antitumor effects by inducing apoptosis and inhibiting the proliferation of different cancer cells; however, the anticancer effects and mechanism of
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