O2389
OMDM-1
≥97% (HPLC), powder
别名:
(N-[(S)-2-Hydroxy-1-(4-hydroxybenzyl)-ethyl]-octadec-9-enoamide
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关于此项目
经验公式（希尔记法）:
C27H45NO3
化学文摘社编号:
分子量:
431.65
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352202
MDL number:
InChI
1S/C27H45NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-27(31)28-25(23-29)22-24-18-20-26(30)21-19-24/h9-10,18-21,25,29-30H,2-8,11-17,22-23H2,1H3,(H,28,31)/b10-9-/t25-/m0/s1
SMILES string
CCCCCCCC\C=C/CCCCCCCC(=O)N[C@H](CO)Cc1ccc(O)cc1
InChI key
ICDMLAQPOAVWNH-JRUKXMRZSA-N
assay
≥97% (HPLC)
form
powder
color
off-white
solubility
DMSO: soluble ~24 mg/mL
Biochem/physiol Actions
Potent, selective inhibitor of anadamide cellular uptake with low affinity for CB1 and CB2 receptors, no activity at VR1 receptor or fatty acid amide hydrolase (FAAH); stable to enzymatic hydrolysis by rat brain homogenates.
Potent, selective inhibitor of anadamide cellular uptake; stable to enzymatic hydrolysis.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Giorgio Ortar et al.
Biochemical pharmacology, 65(9), 1473-1481 (2003-05-07)
Novel aromatic analogues of N-oleoylethanolamine and N-arachidonoylethanolamine (anandamide, AEA) were synthesized and, based on the capability of similar compounds to interact with proteins of the endocannabinoid and endovanilloid signaling systems, were tested on: (i) cannabinoid CB(1) and CB(2) receptors; (ii)
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