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Merck
CN

O5502

S-Octylglutathione

suitable for ligand binding assays

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关于此项目

经验公式(希尔记法):
C18H33N3O6S
化学文摘社编号:
分子量:
419.54
PubChem Substance ID:
UNSPSC Code:
12352209
MDL number:
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产品名称

S-Octylglutathione,

form

solid

technique(s)

ligand binding assay: suitable

storage temp.

2-8°C

SMILES string

CCCCCCCCSCC(NC(=O)CCC(N)C(O)=O)C(=O)NCC(O)=O

InChI

1S/C18H33N3O6S/c1-2-3-4-5-6-7-10-28-12-14(17(25)20-11-16(23)24)21-15(22)9-8-13(19)18(26)27/h13-14H,2-12,19H2,1H3,(H,20,25)(H,21,22)(H,23,24)(H,26,27)

InChI key

MJWCZWAVSJZQNL-UHFFFAOYSA-N

Biochem/physiol Actions

S-octylglutathione is a competitive inhibitor for glutathione S-transferases.


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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M A Tirmenstein et al.
Biochimica et biophysica acta, 995(2), 174-180 (1989-04-06)
Glutathione protects isolated rat liver nuclei against lipid peroxidation by inducing a lag period prior to the onset of peroxidation. This GSH-dependent protection was abolished by exposing isolated nuclei to the glutathione S-transferase inhibitor S-octylglutathione. In incubations containing 0.2 mM
E Ortiz-Salmerón et al.
Biochimica et biophysica acta, 1548(1), 106-113 (2001-07-14)
The binding of three competitive glutathione analogue inhibitors (S-alkylglutathione derivatives) to glutathione S-transferase from Schistosoma japonicum, SjGST, has been investigated by isothermal titration microcalorimetry at pH 6.5 over a temperature range of 15--30 degrees C. Calorimetric measurements in various buffer
G Davidson et al.
Biochemistry, 40(15), 4569-4582 (2001-04-11)
Escherichia coli glyoxalase I (GlxI) is a metalloisomerase that is maximally activated by Ni(2+), unlike other known GlxI enzymes which are active with Zn(2+). The metal is coordinated by two aqua ligands, two histidines (5 and 74), and two glutamates



全球贸易项目编号

货号GTIN
O5502-100MG04061833275764