O6380
[Thr4, Gly7]-Oxytocin
≥97% (HPLC)
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关于此项目
经验公式（希尔记法）:
C39H61N11O12S2
化学文摘社编号:
分子量:
940.10
MDL编号:
UNSPSC代码:
51111800
PubChem化学物质编号:
方案
≥97% (HPLC)
储存温度
−20°C
SMILES字符串
CCC(C)C1NC(=O)C(Cc2ccc(O)cc2)NC(=O)C(N)CSSCC(NC(=O)C(CC(N)=O)NC(=O)C(NC1=O)C(C)O)C(=O)NCC(=O)NC(CC(C)C)C(=O)NCC(N)=O
Amino Acid Sequence
Cys-Tyr-Ile-Thr-Asn-Cys-Gly-Leu-Gly-NH2 [Disulfide Bridge: 1-6]
生化/生理作用
Neuropeptide synthesized in the hypothalamus and involved in the control of lactation and parturition; selective ligand for central and peripheral oxytocin receptors.
Christophe Breton et al.
The Journal of clinical endocrinology and metabolism, 87(3), 1415-1418 (2002-03-13)
In the present report, we provide for the first time evidence that functional oxytocin receptors (OTRs) are present in human myoblasts obtained from clonal cultures of postnatal satellite cells. First, binding studies performed with a non selective vasopressin (AVP) and
P Poulin et al.
Journal of neuroendocrinology, 5(1), 33-39 (1993-02-01)
The recent observation that the central oxytocin (OT) receptor has high affinity for both OT and arginine vasopressin (AVP) raises the possibility that it may be involved in some of the central actions of AVP. Repeated intracerebroventricular (icv) injections of
J Frayne et al.
Biology of reproduction, 52(6), 1268-1273 (1995-06-01)
The effect of the neurohypophysial hormones oxytocin and arginine vasopressin (AVP) on testicular steroidogenesis was reevaluated by use of short-term (< 10 h) cultures of isolated adult rat Leydig cells. Oxytocin at 10(-9), 10(-7), and 10(-5) M concentrations significantly increased
Anissa Benoussaidh et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 287(2), R446-R453 (2004-03-27)
The rat uterus receives an innervation from the lumbosacral and thoracolumbar segments of the spinal cord. These segments receive descending oxytocinergic projections from the paraventricular nucleus of the hypothalamus. We tested the hypothesis that oxytocin regulates uterine motility through a
M A Petty et al.
European journal of pharmacology, 112(2), 203-210 (1985-06-07)
In conscious, chronically instrumented normotensive male Wistar rats intravenous (i.v.) administration of oxytocin (OXT) (greater than or equal to 100 ng) induced a dose-related biphasic change in mean arterial pressure (MAP). This consisted of an initial pressor effect accompanied by
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