O9262
1-O-Octadecyl-2-O-methyl-sn-glycero-3-phosphorylcholine
≥99% (TLC), waxy solid
别名:
ET-18-OCH3
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C27H58NO6P
分子量:
523.73
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352202
MDL number:
InChI key
MHFRGQHAERHWKZ-HHHXNRCGSA-N
SMILES string
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC)COCCCCCCCCCCCCCCCCCC)=O
InChI
1S/C27H58NO6P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-23-32-25-27(31-5)26-34-35(29,30)33-24-22-28(2,3)4/h27H,6-26H2,1-5H3/t27-/m1/s1
assay
≥99% (TLC)
form
waxy solid
color
white
solubility
ethanol: soluble 15 mg/mL at 45 °C, chloroform: soluble >25 mg/mL, DMSO: soluble
shipped in
wet ice
storage temp.
−20°C
正在寻找类似产品? 访问 产品对比指南
Biochem/physiol Actions
Phosphoinositide-specific phospholipase C (PI-PLC) inhibitor.
Features and Benefits
This compound is featured on the Phospholipase C page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Preparation Note
1-O-Octadecyl-2-O-methyl-sn-glycero-3- phosphorylcholine is soluble in ethanol at 15 mg/ml and in chloroform at 25 mg/ml.
The following steps are for the preparation of a DMSO stock solution.
1. Solubilize 1-O-Octadecyl-2-O-methyl-sn-glycero-3-phosphorylcholine in chloroform.
2. Deposit a thin film of the compound on the sides of a container by evaporating the chloroform with a stream of nitrogen or argon.
3. Add DMSO and vortex mix to dissolve the compound from the sides of the container. The DMSO or ethanol solutions may be diluted at least 1000-fold directly into stirred aqueous cell culture medium.
The following steps are for the preparation of a DMSO stock solution.
1. Solubilize 1-O-Octadecyl-2-O-methyl-sn-glycero-3-phosphorylcholine in chloroform.
2. Deposit a thin film of the compound on the sides of a container by evaporating the chloroform with a stream of nitrogen or argon.
3. Add DMSO and vortex mix to dissolve the compound from the sides of the container. The DMSO or ethanol solutions may be diluted at least 1000-fold directly into stirred aqueous cell culture medium.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
I Baburina et al.
The Journal of biological chemistry, 273(4), 2169-2173 (1998-01-27)
A HeLa cell line was constructed for the regulation of CTP:phosphocholine cytidylyltransferase (CCT) expression via a tetracycline-responsive promoter to test the role of CCT in apoptosis triggered by exposure of cells to the antineoplastic phospholipid 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine (ET-18-OCH3). Basal CCT expression
Kei Tamura et al.
Molecular and cellular biochemistry, 398(1-2), 73-81 (2014-09-10)
In anuran amphibians, larval red blood cells (RBCs) are replaced by adult-type RBCs during metamorphosis. We previously showed that tumor necrosis factor-related apoptosis-inducing ligand 1 (TRAIL1) induces apoptosis in larval-, but not adult-type RBCs in Xenopus laevis. We also found
Vítezslav Bryja et al.
Journal of cell science, 120(Pt 4), 586-595 (2007-01-25)
Previously, we have shown that Wnt-5a strongly regulates dopaminergic neuron differentiation by inducing phosphorylation of Dishevelled (Dvl). Here, we identify additional components of the Wnt-5a-Dvl pathway in dopaminergic cells. Using in vitro gain-of-function and loss-of-function approaches, we reveal that casein
M R Pabbidi et al.
PloS one, 11(12), e0168505-e0168505 (2016-12-16)
We previously reported in atrial myocytes that inhibition of cAMP-dependent protein kinase (PKA) by laminin (LMN)-integrin signaling activates β2-adrenergic receptor (β2-AR) stimulation of cytosolic phospholipase A2 (cPLA2). The present study sought to determine the signaling mechanisms by which inhibition of
Cristián Ibarra et al.
Molecular oncology, 13(2), 202-211 (2018-10-26)
Bacillus Calmette-Guérin (BCG) is widely used in the clinic to effectively treat superficial urinary bladder cancer. However, a significant proportion of patients who fail to respond to BCG risk cystectomy or death. Though more than 3 million cancer treatments with
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持