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Merck
CN

P0307

Poly(deoxyadenylic-deoxycytidylic) acid • Poly(deoxyguanylic-thymidylic) acid sodium salt

别名:

Poly(2′-deoxyadenyl-2′-deoxycytidylicacid) · Poly(2′-deoxyguanylthymidylic acid) sodium salt, Poly(dA-dC) • Poly(dG-dT) sodium salt

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化学文摘社编号:
UNSPSC Code:
41106305
MDL number:
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storage temp.

−20°C

Application

Poly(deoxyadenylic-deoxycytidylic) acid • Poly(deoxyguanylic-thymidylic) acid (Poly(dA-dC) • Poly(dG-dT)) is a double-stranded alternating copolymer DNA model for conformational studies of DNA structure dynamics and drug interaction.

Other Notes

Double-stranded alternating copolymer; model for conformational studies of DNA.
One unit will yield an A260 of 1.0 in 1.0 ml of 0.1 M NaCl and 0.01 M potassium phosphate, pH 7.0 (1 cm light path).


存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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Ville Laitala et al.
Analytical chemistry, 77(5), 1483-1487 (2005-03-01)
We report here a novel, time-resolved, lanthanide-based energy-transfer assay utilizing nonoverlapping acceptor fluorophores, which have their absorption energetically at a higher level than the emittive transitions of the donor. The technique was studied by comparing a series of nonoverlapping acceptors
Anil Kumar et al.
Chemphyschem : a European journal of chemical physics and physical chemistry, 10(9-10), 1426-1430 (2009-03-25)
Low-energy electrons (LEEs) interact with a DNA model system to create a variety of excited states. In the gas phase, dissociative (sigma*) states are accessible by LEEs with energy <4 eV (see picture) and cause facile strand breaks through a
Chris T Middleton et al.
Annual review of physical chemistry, 60, 217-239 (2008-11-18)
Ultraviolet light is strongly absorbed by DNA, producing excited electronic states that sometimes initiate damaging photochemical reactions. Fully mapping the reactive and nonreactive decay pathways available to excited electronic states in DNA is a decades-old quest. Progress toward this goal