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Merck
CN

P0319

Sigma-Aldrich

2-花生四烯酰-1-棕榈酰-sn-甘油-3-磷酸胆碱

10 mg/mL in chloroform

别名:

1-十六酰-2-([顺,顺,顺,顺]-5,8,11,14-二十碳四烯酰)-sn-甘油-3-磷酸胆碱, L-α-磷脂酰胆碱 β-花生四烯酰-γ-棕榈酰

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关于此项目

经验公式（希尔记法）:
C44H80NO8P
化学文摘社编号:
35418-58-7
分子量:
782.08
MDL编号:
MFCD00171671
UNSPSC代码:
12352211
PubChem化学物质编号:
329820031

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浓度

10 mg/mL in chloroform

官能团

phospholipid

运输

dry ice

储存温度

−20°C

SMILES字符串

CCCCCCCCCCCCCCCC(=O)O[C@H](COC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC)COP([O-])(=O)OCC[N+](C)(C)C

InChI

1S/C44H80NO8P/c1-6-8-10-12-14-16-18-20-21-22-23-25-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-24-19-17-15-13-11-9-7-2/h14,16,20-21,23,25,28,30,42H,6-13,15,17-19,22,24,26-27,29,31-41H2,1-5H3/b16-14-,21-20-,25-23-,30-28-/t42-/m1/s1

InChI key

PUDHBQQGURLBGJ-IVFHWKNFSA-N

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象形图

Skull and crossbonesHealth hazard
GHS06,GHS08

警示用语：

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

靶器官

Central nervous system

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

易制毒化学品（2类）
危险化学品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
090K5226
066H8386
066H8359
043H84522
039H5189

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N Leitinger et al.
Advances in experimental medicine and biology, 433, 379-382 (1997-01-01)
Our group has previously demonstrated that oxidized phospholipids derived from mildly oxidized low density lipoprotein (MM-LDL) or oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine (oxPAPC) increase monocyte-endothelial interactions. There are indications that the effects of these phospholipids are receptor mediated. Oxidized phospholipids have previously been
N Leitinger et al.
Proceedings of the National Academy of Sciences of the United States of America, 96(21), 12010-12015 (1999-10-16)
We previously have demonstrated that oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine (OxPAPC), a component of minimally modified low density lipoprotein (MM-LDL), activates endothelial cells to bind monocytes. 1-Palmitoyl-2- (5-oxovaleroyl)-sn-glycero-3-phosphorylcholine (POVPC) and 1- palmitoyl-2-glutaroyl-sn-glycero-3-phosphorylcholine (PGPC), which are present in OxPAPC, MM-LDL, and atherosclerotic lesions, were
S Paglin et al.
The Journal of biological chemistry, 268(16), 11697-11702 (1993-06-05)
Hormonally regulated and particulate-associated phospholipase A2 (PLA2) was detected in endothelial cells from bovine pulmonary artery. The enzyme was solubilized and subjected to initial characterization. PLA2 activity was determined in subcellular fractions from bradykinin (BK)-stimulated and nonstimulated cells by following
Salam Ibrahim et al.
Journal of lipid research, 47(2), 341-348 (2005-11-19)
LDL-associated phospholipids (PLs) may be transferred into platelets. In this work, we characterized the role of VLDLs as PL donors. VLDL transferred radiolabeled PLs to platelets in a temperature- and concentration-dependent manner. LPL stimulated this process through its action on
John E Burke et al.
The Journal of biological chemistry, 283(45), 31227-31236 (2008-08-30)
The Group IVA (GIVA) phospholipase A(2) associates with natural membranes in response to an increase in intracellular Ca(2+) along with increases in certain lipid mediators. This enzyme associates with the membrane surface as well as binding a single phospholipid molecule
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