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Merck
CN

P0391

5α-孕烷-3β,11β,21-三醇-20-酮

别名:

3β,11β,21-三羟基-5α-孕甾-20-酮, 3β,5α-四氢皮质甾酮, 3β-别四氢皮质甾酮, Reichstein 物质 R, 别孕烷-3β,11β,21-三醇-20-酮

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关于此项目

经验公式(希尔记法):
C21H34O4
化学文摘社编号:
分子量:
350.49
UNSPSC Code:
41116107
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technique(s)

HPLC: suitable, gas chromatography (GC): suitable

format

neat

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

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Y B Saalmann et al.
Journal of neuroendocrinology, 19(4), 272-284 (2007-03-16)
The 3alpha-hydroxy,5alpha-reduced pregnane steroids, allopregnanolone and allotetrahydrodeoxycorticosterone, are the most potent endogenous positive modulators of GABA(A) receptor-mediated inhibition. This study presents the first immunohistochemical examination of the cellular distribution of 3alpha-hydroxy,5alpha-reduced pregnane steroids across the brain. We found a widespread
A Soro et al.
Journal of human hypertension, 9(6), 391-393 (1995-06-01)
In a large group of patients with untreated hypertension, excretion rates of tetrahydrocorticosterone (THB), allotetrahydrocorticosterone (alloTHB) and tetrahydro-11-dehydrocorticosterone (THA) were all significantly higher than in a group of matched normotensive controls. Using the sum of these metabolites as an index
Kendall D W Morris et al.
Molecular pharmacology, 66(1), 56-69 (2004-06-24)
Rho(1) receptor-channels (rho(1)Rs) are GABA-gated chloride channels that exhibit slow kinetics, little desensitization, and inert pharmacology to most anesthetics, except for neuroactive steroids (NSs). NSs differentially modulate rho(1)Rs dependent on the steric arrangement of the hydrogen atom at the fifth
L Trachsel et al.
The European journal of neuroscience, 8(2), 319-328 (1996-02-01)
Infrared light transmittance imaging was used in rat hypothalamic slices to record an intrinsic optical signal (IOS) of the cell ensemble in the suprachiasmatic nuclei (SCN), the locus of the endogenous circadian clock. Upon optic chiasm stimulation, a transient IOS
R A Tigranian et al.
Endocrinologia experimentalis, 14(1), 3-7 (1980-03-01)
The urinary excretion of 17-hydroxycorticosteroids and the relations between the glucocorticoids in urine and their precursors as well as between 17-hydroxycorticoids and 17-hydroxycorticoids and 17-dehydroxycorticosteroids was measured in two subjects before and after 8 days flight in spaceship "Soyuz-22". During

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