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Merck
CN

P1152

聚(Ala, Glu, Lys, Tyr) 6:2:5:1 氢溴酸盐

greener alternative

Ala:Glu:Lys:Tyr (6:2:5:1), mol wt 20,000-30,000

别名:

(L-Ala, L-Glu, L-Lys, L-Tyr)n ·HBr, COP-1

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化学文摘社编号:
UNSPSC Code:
12352202
NACRES:
NA.26
MDL number:
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产品名称

聚(Ala, Glu, Lys, Tyr) 6:2:5:1 氢溴酸盐, Ala:Glu:Lys:Tyr (6:2:5:1), mol wt 20,000-30,000

SMILES string

N[C@@H](CCCCN)C(=O)O.N[C@@H](Cc1ccc(cc1)O)C(=O)O.N[C@@H](CCC(=O)O)C(=O)O.N[C@@H](C)C(=O)O

InChI

1S/C9H11NO3.C6H14N2O2.C5H9NO4.C3H7NO2/c10-8(9(12)13)5-6-1-3-7(11)4-2-6;7-4-2-1-3-5(8)6(9)10;6-3(5(9)10)1-2-4(7)8;1-2(4)3(5)6/h1-4,8,11H,5,10H2,(H,12,13);5H,1-4,7-8H2,(H,9,10);3H,1-2,6H2,(H,7,8)(H,9,10);2H,4H2,1H3,(H,5,6)/t8-;5-;3-;2-/m0000/s1

InChI key

YLOCGHYTXIINAI-XKUOMLDTSA-N

form

powder

feed ratio

Ala:Glu:Lys:Tyr (6:2:5:1)

mol wt

20,000-30,000

greener alternative product score

old score: 56
new score: 39
Find out more about DOZN™ Scoring

greener alternative product characteristics

Designing Safer Chemicals
Safer Solvents and Auxiliaries
Reduce Derivatives
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

color

white to off-white

greener alternative category

storage temp.

−20°C

Quality Level

Analysis Note

基于粘度报告的分子量。

Biochem/physiol Actions

聚(Ala,Glu,Lys,Tyr)6:2:5:1氢溴酸盐是一种聚氨基酸,据报道对过敏性脑脊髓炎具有抑制作用。
据报道对实验动物诱发的实验性变态反应性脑脊髓炎有抑制作用。

General description

我们竭诚为您带来满足绿色替代产品四大类别要求的替代产品。本品属于重新设计产品类别,在“设计更安全的化学品”、“更安全的溶剂和助剂”以及“减少衍生物”绿色化学原则方面取得了重大进步。 点击此处查看其 DOZN 记分卡。

Other Notes

有关聚氨基酸的其他技术信息,请访问 聚氨基酸常见问题解答资源

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

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M Sela et al.
Israel journal of medical sciences, 31(1), 10-12 (1995-01-01)
Expanded clinical trials of treatments for multiple sclerosis: copolymer 1 (COP-1) treatment investigational new drug (IND) program.
Y Stark
Annals of neurology, 36(1), 114-115 (1994-07-01)
Carmen C M Chan
Recent patents on CNS drug discovery, 3(3), 189-199 (2008-11-11)
Spinal cord injury leads to a devastating cascade of secondary complications that eventually results in the formation of scar tissue many times the size of the original insult. Inflammation plays a very important role towards the development of such scar
E Zisman et al.
European journal of immunology, 24(10), 2497-2505 (1994-10-01)
Studies with the well-characterized, synthetic, random-multichain polypeptide poly(LTyr,LGlu)-poly(DLAla)-poly(LLys) (T,G)-A-L) led to the discovery of determinant-specific genetic control of the immune response, as well as to other immunological phenomena. Moreover, the tetrapeptide TyrTyrGluGlu built on the same backbone ("(T-T-G-G)-A--L") was found
Byoung-Joo Choi et al.
Japanese heart journal, 45(4), 697-702 (2004-09-09)
A 16 year-old Korean girl with cardiomegaly was found to have a "right atrial cystic mass" on transthoracic echocardiography. An unusual cystic structure made the diagnosis difficult. However, transesophageal echocardiography and multidetector computed tomography revealed a coronary artery fistula with

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