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Merck
CN

P1490

Pepsinogen I human

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化学文摘社编号:
UNSPSC Code:
12352202
MDL number:
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biological source

human

form

liquid

specific activity

≥500 U/mg (Lowry)

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

Gene Information

Biochem/physiol Actions

Studies show that smoking has an effect on the level of pepsinogen I present in serum in a H. pylori-dependent manner. Patients with lower titer levels had higher levels of pepsinogen I.
Used as a control in ELISA.

Physical form

0.2 μm filtered solution in Tris chloride, pH 8.5

Other Notes

One unit will produce a delta A280 of 0.001 per min at pH 2.0 at 37 deg C, measured as TCA-soluble products using hemoglobin as substrate. (Final Volume of reaction mixture = 16mL, 1 cm light path)


存储类别

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

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M Tatemichi et al.
Japanese journal of cancer research : Gann, 92(3), 243-248 (2001-03-27)
Serum pepsinogen (sPG) levels are used in gastric cancer screening programs. However, modification of sPG levels by smoking habit, according to the status of Helicobacter pylori (H. pylori) infection has been little investigated. This study investigated the effects of smoking