P1494
Monoclonal Anti-PMCA4 antibody produced in mouse
~1 mg/mL, clone JA9, purified immunoglobulin, buffered aqueous solution
别名:
Anti-Plasma Membrane Calcium ATPase 4
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关于此项目
Conjugate:
unconjugated
Clone:
JA9, monoclonal
Application:
ELISA (i), IHC, WB
Citations:
3
form
buffered aqueous solution
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
JA9, monoclonal
species reactivity
human, rat
concentration
~1 mg/mL
technique(s)
immunohistochemistry: suitable, indirect ELISA: 1:15,000 using human or rat tissue, western blot: 1:1,000 using human or rat tissue
isotype
IgG1
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... ATP2B4(493)
Immunogen
purified human erythrocyte PMCA.
Physical form
Solution in phosphate buffered saline containing 1 mg/ml bovine serum albumin and 0.05 % sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Randa Naffa et al.
Cancers, 13(6) (2021-04-04)
We demonstrated that the plasma membrane Ca2+ ATPase PMCA4b inhibits migration and metastatic activity of BRAF mutant melanoma cells. Actin dynamics are essential for cells to move, invade and metastasize, therefore, we hypothesized that PMCA4b affected cell migration through remodeling
Karolina Varga et al.
Cell calcium, 55(2), 78-92 (2014-01-21)
The expression of the plasma membrane Ca2+ ATPase (PMCA) isoforms is altered in several types of cancer cells suggesting that they are involved in cancer progression. In this study we induced differentiation of MCF-7 breast cancer cells by histone deacetylase
Randa Naffa et al.
Cells, 9(5) (2020-05-18)
Metastatic melanoma is the most aggressive type of skin cancer. Previously, we identified the plasma membrane Ca2+ pump isoform 4b (PMCA4b or ATP2B4) as a putative metastasis suppressor in BRAF mutant melanoma cells. Metastasis suppressors are often downregulated in cancer
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