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Merck
CN

P1527

1,2-Di-O-hexadecyl-sn-glycero-3-phosphocholine

≥99% (TLC)

别名:

(7R)-7-(Hexadecyloxy)-4-hydroxy-N,N,N-trimethyl-3,5,9-trioxa-4-phosphapentacosan-1-aminium 4-oxide, inner salt, 1-Hexadecyl-2-hexadecyl-sn-glycero-3-phosphocholine, 3-sn-Phosphatidylcholine, 1,2-dihexadecyl, L-α-Lecithin dihexadecyl ether, L-α-Phosphatidylcholine, di-O-hexadecyl, L-β,γ-Dihexadecyl-α-lecithin, DCPC, Glycerol-3-sn-phosphorylcholine 1,2-bis(hexadecyl ether), PC(O-16:0/O-16:0)

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关于此项目

经验公式(希尔记法):
C40H84NO6P
化学文摘社编号:
分子量:
706.07
UNSPSC Code:
12352211
NACRES:
NA.25
PubChem Substance ID:
EC Number:
252-968-0
Beilstein/REAXYS Number:
4168071
MDL number:
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InChI key

DACAUPQETXAEBT-UHFFFAOYSA-N

InChI

1S/C40H85NO6P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-35-44-38-40(39-47-48(42,43)46-37-34-41(3,4)5)45-36-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h40H,6-39H2,1-5H3,(H,42,43)

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OCCCCCCCCCCCCCCCC)COCCCCCCCCCCCCCCCC)=O

assay

≥99% (TLC)

form

powder

functional group

phospholipid

lipid type

phosphoglycerides

shipped in

ambient

storage temp.

−20°C

Application

1,2-Di-O-hexadecyl-sn-glycero-3-phosphocholine (DHPC) may be suitable for use in coating hydrophobic styrene-divinylbenzene. It may also be suitable for spreading onto the subphase to form monolayer to perform penetration studies of phospholipase A2 (PLA2).

Biochem/physiol Actions

1,2-Di-O-hexadecyl-sn-glycero-3-phosphocholine (DHPC) is a nonhydrolyzable ether analog of phosphocholine.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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分析证书(COA)

Lot/Batch Number

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A Structure-Function Study of the C2 Domain of Cytosolic Phospholipase A2 IDENTIFICATION OF ESSENTIAL CALCIUM LIGANDS AND HYDROPHOBIC MEMBRANE BINDING RESIDUES
Bittova L, et al.
The Journal of biological chemistry, 274(14), 9665-9672 (1999)
Roles of Trp31 in high membrane binding and proinflammatory activity of human group V phospholipase A2
Han SK, et al.
The Journal of biological chemistry, 274(17), 11881-11888 (1999)
Maria Oranges et al.
Chemistry and physics of lipids, 212, 130-137 (2018-02-08)
Electron spin echo envelope modulation (ESEEM) and conventional electron paramagnetic resonance (EPR) of site-specifically spin-labelled phospholipids are used to investigate the effect of ether-linked chains on the water-penetration and polarity profiles, as well as the phase behaviour and chain flexibility

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