表单
solid
颜色
white
储存温度
2-8°C
生化/生理作用
Subunit of pertussis toxin responsible for binding to cell surfaces; stimulates both platelet aggregation and cytosolic Ca2+ level elevation, may also activate phospholipase C; isolated from B pertussis strain 165.
制备说明
Each vial contains 40 μg of protein which may be reconstituted with either sterile distilled water or sterile buffer.
免责声明
Do not freeze. Do not subject to sterile filtration, as this will result in loss of material.
警示用语：
Danger
危险分类
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral
储存分类代码
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
法规信息
新产品
此项目有
M Tamura et al.
The Journal of biological chemistry, 258(11), 6756-6761 (1983-06-10)
Islet-activating protein (IAP), pertussis toxin, is an oligomeric protein (Tamura, M., Nogimori, K., Murai, S., Yajima, M., Ito, K., Katada, T., Ui, M., and Ishii, S. (1982) Biochemistry 21, 5516-5522), the biggest subunit (Mr = 28,000, referred to as the
C F Strnad et al.
FEBS letters, 225(1-2), 16-20 (1987-12-10)
Pertussis toxin was found to serve as a mitogen in the human T lymphocyte, an effect which could be mimicked by its resolved binding component, the B oligomer. The mechanism of action of this component appeared to involve a rapid
H S Banga et al.
The Journal of biological chemistry, 262(31), 14871-14874 (1987-11-05)
The activation of phospholipase C in human platelets is coupled to agonist receptors via guanine nucleotide-binding protein(s), and prior treatment of permeabilized platelets with GTP gamma S, GDP beta S, or pertussis toxin modifies platelet responses to agonists. Pertussis toxin
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