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Merck
CN

P1740

Sigma-Aldrich

Protein Phosphatase 2A1 from rabbit muscle

≥95%, ~2000 units/mg protein, solution

别名:

PP2A1

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MDL编号:
UNSPSC代码:
12352204
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方案

≥95%

表单

solution

比活

~2000 units/mg protein

分子量

187 kDa (Based on subunit composition A.B.C2 (A= 60 kDa, B=55 kDa, C=36 kDa))

运输

dry ice

储存温度

−20°C

生化/生理作用

Protein phosphatase 2A1 is specific for phosphorylated serine and threonine residues, with a preference for sites in signal transduction kinases.

其他说明

One unit equals 1 nanomole of phosphate relased per minute from 15 mM phosphorylase A

法规信息

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D B DeFranco et al.
Molecular endocrinology (Baltimore, Md.), 5(9), 1215-1228 (1991-09-01)
We have used okadaic acid (OA), a cell-permeable inhibitor of serine/threonine protein phosphatase types 1 (PP-1) and 2A (PP-2A), to demonstrate that the subcellular distribution of glucocorticoid receptor (GR) in rat fibroblasts is influenced by its phosphorylation state. Nuclear GRs
A Ito et al.
The EMBO journal, 19(4), 562-571 (2000-02-17)
Both F10 and BL6 sublines of B16 mouse melanoma cells are metastatic after intravenous injection, but only BL6 cells are metastatic after subcutaneous injection. Retrotransposon insertion was found to produce an N-terminally truncated form (Deltagamma1) of the B56gamma1 regulatory subunit

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