biological source
whole wheat flour
form
lyophilized powder
specific activity
0.25-1.0 units/mg protein
composition
Protein, ~90%
UniProt accession no.
storage temp.
−20°C
Gene Information
wheat ... Pur-B1(543304)
Biochem/physiol Actions
In conjunction with thioredoxin, affects proper protein folding; cytotoxic, presumably by forming pores in cytoplasmic membrane.
Other Notes
One unit will cause a ΔA650 of 1.0 per min (increase the turbidity) of a 1 mg/ml solution of bovine insulin in the presence of 2 mM EDTA and 0.33 mM DTT at pH 7.5 at 37 °C.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
S Orrù et al.
Biological chemistry, 378(9), 989-996 (1997-11-05)
The complete primary structure of a cytotoxic 5 kDa polypeptide, viscotoxin A1, isolated from Viscum album L., has been determined by combining classical Edman degradation methodology with advanced mass spectrometric procedures. The same integrated approach allowed correction of the sequence
Svetlana Oard et al.
Biophysical chemistry, 121(1), 30-43 (2006-01-24)
Wheat beta-purothionin is a highly potent antimicrobial peptide which, however, is inactivated by metal ions. The key structural properties and mechanisms of inhibition of beta-purothionin were investigated for the first time using unconstrained molecular dynamics simulations in explicit water. A
Antimutagens (β-purothionin and crown compound) as modulators of expression of genes involved in carcinogenesis in human cells.
G D Zasukhina et al.
Doklady. Biochemistry and biophysics, 446, 254-256 (2012-11-08)
Luke A Clifton et al.
Physical chemistry chemical physics : PCCP, 13(38), 17153-17162 (2011-08-27)
The indolines and thionins are basic, amphiphilic and cysteine-rich proteins found in cereals; puroindoline-a (Pin-a) and β-purothionin (β-Pth) are members of these families in wheat (Triticum aestivum). Pin-a and β-Pth have been suggested to play a significant role in seed
A Büssing et al.
Anticancer research, 18(6A), 4291-4296 (1999-01-19)
Extracts from Viscum album L. are widely used as an adjuvant in complementary cancer therapy. While the mechanisms of mistletoe lectin (ML) cytotoxicity are well described, the viscotoxin (VT) effects are unclear at present. Thus, we treated human lymphocytes with
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持