P220
Peptide YY Fragment 3-36 human
≥95% (HPLC), lyophilized powder
Amino Acid Sequence
Ile-Lys-Pro-Glu-Ala-Pro-Gly-Glu-Asp-Ala-Ser-Pro-Glu-Glu-Leu-Asn-Arg-Tyr-Tyr-Ala-Ser-Leu-Arg-His-Tyr-Leu-Asn-Leu-Val-Thr-Arg-Gln-Arg-Tyr-NH2
一般描述
Human peptide YY (PYY) is a 36 amino acid peptide secreted by mucosal L cells in the distal ileum, colon and rectum. The gene encoding PYY is localized on human chromosome 17q21.1.
生化/生理作用
Y2/Y5 Neuropeptide Y receptor agonist. Human peptide YY (PYY) has roles in energy homeostasis, food ingestion, gut motility and insulin secretion. The protein suppresses appetite. It has been associated with obesity and type 2 diabetes.
包装
Bottomless glass bottle. Contents are inside inserted fused cone.
免责声明
吸湿
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
M Gué et al.
British journal of pharmacology, 118(2), 237-242 (1996-05-01)
1. The Y receptor subtype involved in the antagonism by neuropeptide Y (NPY) of intracisternal corticotropin-releasing factor (CRF)-induced inhibition of gastric acid secretion was studied in urethane-anaesthetized rats by use of peptides with various selectivity for Y1, Y2 and Y3
R Abounader et al.
British journal of pharmacology, 116(4), 2245-2250 (1995-10-01)
1. We have characterized pharmacologically the receptor subtype(s) responsible for the neuropeptide Y (NPY)-induced vasoconstriction in human cerebral arteries. NPY, PYY and several of their derivatives with well defined affinities at the known Y1 and Y2 receptor subtypes were used.
Genomic and gene expression signature of the pre-invasive
testicular carcinoma in situ
testicular carcinoma in situ
Kristian Almstrup
Cell and Tissue Research (2005)
TLR ligands and butyrate increase Pyy expression through two distinct but inter-regulated pathways.
Larraufie P
Cellular Microbiology (2017)
Expression of peptide YY by human blood leukocytes.
Holler JP
Peptides (2014)
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