assay
~95% (SDS-PAGE)
form
lyophilized powder
specific activity
~40,000 units/mg protein (Lowry)
mol wt
16.8 kDa
impurities
salt, essentially free
UniProt accession no.
storage temp.
−20°C
Gene Information
cow ... CALM3(520277)
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Biochem/physiol Actions
环核苷酸依赖性磷酸二酯酶活化所需的 Ca2+ 结合蛋白。它也是一氧化氮合成酶、钙调磷酸酶以及多种激酶的辅因子/活化剂,这些激酶包括 ATP 酶、肌球蛋白轻链激酶和 CAM 激酶 I、II、III。它通过环二磷酸腺苷核糖介导利阿诺定受体活化并且与细胞内 Ca2+ 的内稳态有关。
钙调素是 Ca2+ 依赖性调节蛋白 (CDR),肌钙蛋白 C 样蛋白。
Other Notes
在存在 0.01mM Ca2+ 以及 pH 7.5 和 30°C 下,一单位本品能激活 3ml 反应体积中 0.008 个活化单位的 3′:5′-环核苷酸磷酸二酯酶,并且当用活化剂使这种酶饱和时能达到最大酶活性的 50%。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
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Renaud Léguillette et al.
American journal of physiology. Cell physiology, 295(3), C653-C660 (2008-07-11)
Smooth muscle is unique in its ability to maintain force at low MgATP consumption. This property, called the latch state, is more prominent in tonic than phasic smooth muscle. Studies performed at the muscle strip level have suggested that myosin
Paula Ramos-Silva et al.
PloS one, 9(6), e97454-e97454 (2014-06-04)
The scleractinian coral Acropora millepora is one of the most studied species from the Great Barrier Reef. This species has been used to understand evolutionary, immune and developmental processes in cnidarians. It has also been subject of several ecological studies
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