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Merck
CN

P2905

Sigma-Aldrich

[Nle8,18, Tyr34]-PTH Fragment 1-34 amide bovine

≥97% (HPLC)

别名:

Ala-Val-Ser-Glu-Ile-Gln-Phe-Nle-His-Asn-Leu-Gly-Lys-His-Leu-Ser-Ser-Nle-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Tyr-NH2

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经验公式(希尔记法):
C185H293N55O50
化学文摘社编号:
分子量:
4087.64
MDL编号:
UNSPSC代码:
12352200
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方案

≥97% (HPLC)

表单

powder

储存温度

−20°C

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

新产品
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历史批次信息供参考:

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J Lafond et al.
Endocrinology, 123(6), 2834-2840 (1988-12-01)
The syncytiotrophoblast of the placenta is the site of exchange of nutrients and minerals between the mother and fetus. We have recently demonstrated that PTH influences, in vitro, phosphate transport through the placenta brush border membranes (BBM) and increases cAMP
I Yamamoto et al.
Endocrinology, 122(4), 1208-1217 (1988-04-01)
PTH receptors on two stable clonal rat osteosarcoma cell lines, ROS 17/2 and ROS 17/2.8, were characterized using an HPLC-purified, synthetic, sulfur-free, radioiodinated analog of bovine PTH, [Nle8,Nle18,Tyr,34]bovine PTH-(1-34)amide. PTH binding is specific for PTH agonists and antagonists and is
M Rosenblatt et al.
Endocrine research communications, 4(2), 115-133 (1977-01-01)
Three analogues of bovine parathyroid hormone (bPTH), [Tyr-34]bPTH-(1--34) amide, [Nle-8,Nle-18,Tyr-34]bPTH-(1--34)amide, and [Nle-8,Nle-18, o-NPS-Trp-23,Tyr-34]bPTH-(1--34)amide were synthesized by the solid-phase method. The synthetic peptides were found to be homogeneous in multiple analytical systems. These analogues represent the NH2-terminal one-third of the hormone
M J Atkinson et al.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2(4), 303-309 (1987-08-01)
The in vitro mitotic response of rat thymic lymphocytes to hPTH(1-34), hPTH (1-38), and 8,18 Nle hPTH(1-34) exhibits a dependency upon extracellular calcium. Removal of extracellular calcium or the addition of Verapamil (5 micrograms/ml) or trifluoroperazine (10 microM) abrogated the
J J Helwig et al.
Comparative biochemistry and physiology. A, Comparative physiology, 88(2), 349-354 (1987-01-01)
The effect of [Nle8,18,Tyr34]bPTH-(1-34)amide on renal plasma membrane adenylate cyclase, in the presence of 0.1 mM guanylylimidodiphosphate was measured in rat, chicken, frog and trout. All species showed an enrichment of at least 8-fold (relative to homogenate) in the marker

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