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Merck
CN

P3553

Penicillinase from Escherichia coli 205 TEM R+ (566)

lyophilized powder, 100-300 units/mg solid (using benzylpenicillin), 20-40 units/mg solid (using cephaloridine.)

别名:

β-Lactamase I, β-Lactamase II, Cephalosporinase, Penicillin amido-β-lactam hydrolase

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UNSPSC Code:
12352204
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form

lyophilized powder

specific activity

100-300 units/mg solid (using benzylpenicillin), 20-40 units/mg solid (using cephaloridine.)

storage temp.

2-8°C

Analysis Note

Vial contains 50-100 benzylpenicillin units.

Other Notes

One unit will hydrolyze 1.0 μmole of benzylpenicillin per min at pH 7.0 at 25° C. This International Unit (using benzylpenicillin as substrate) is approximately equal to 600 Levy or 75 Pollock units.

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Despina Kotsanas et al.
The Medical journal of Australia, 198(5), 267-269 (2013-03-19)
Clinical utility of carbapenem antibiotics is under threat because of the emergence of acquired metallo-β-lactamase (MBL) genes. We describe an outbreak in an intensive care unit (ICU) possibly associated with contaminated sinks. Four clusters of gram-negative bacteria harbouring the MBL
Siriluck Anunnatsiri et al.
The Southeast Asian journal of tropical medicine and public health, 43(5), 1169-1177 (2013-02-26)
Escherichia coli producing extended spectrum beta-lactamase (ESBL) has emerged as a worldwide, public health problem. The aims of this study were to determine the incidence of ESBL-producing E. coli septicemia and evaluate the factors associated with the infection and the
Teerawit Tangkoskul et al.
The Southeast Asian journal of tropical medicine and public health, 43(6), 1461-1469 (2013-02-19)
We performed extended-spectrum beta-lactamase (ESBL) phenotypic testing and molecular characterization of three ESBL genes (TEM, SHV and CTX-M) and susceptibility testing by Clinical Laboratory Standards Institute (CLSI) disk diffusion method against three cephalosporins (ceftriaxone, ceftazidime, cefepime) and a cephamycin (cefoxitin)
Grace Yim et al.
Canadian journal of microbiology, 59(2), 110-116 (2013-03-07)
Microbial populations in wastewater treatment plants (WWTPs) are increasingly being recognized as environmental reservoirs of antibiotic resistance genes. PCR amplicons for plasmid-mediated quinolone resistance determinants qnrA, qnrB, and qnrS were recorded in samples from a WWTP in Vancouver, British Columbia.
MMWR. Morbidity and mortality weekly report, 62(6), 108-108 (2013-02-15)
On August 16, 2012, the Colorado Department of Public Health and Environment was notified of two patients at an acute-care hospital in Denver with carbapenem-resistant Enterobacteriaceae (CRE), specifically Klebsiella pneumoniae (CRKP), isolated from respiratory specimens during July-August. Both isolates produced

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