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Merck
CN

P3766

Phorbol 12-myristate 13-acetate 4-O-methyl ether

别名:

MPMA

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关于此项目

经验公式（希尔记法）:
C37H58O8
化学文摘社编号:
57716-89-9
分子量:
630.85
UNSPSC Code:
12352211
NACRES:
NA.25
PubChem Substance ID:
24898450
MDL number:
MFCD00036790
Beilstein/REAXYS Number:
6554604

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InChI

1S/C37H58O8/c1-8-9-10-11-12-13-14-15-16-17-18-19-30(40)44-33-25(3)36(42)28(31-34(5,6)37(31,33)45-26(4)39)21-27(23-38)22-35(43-7)29(36)20-24(2)32(35)41/h20-21,25,28-29,31,33,38,42H,8-19,22-23H2,1-7H3/t25-,28+,29-,31-,33-,35-,36-,37-/m1/s1

SMILES string

CCCCCCCCCCCCCC(=O)O[C@@H]1[C@@H](C)[C@@]2(O)C(C=C(CO)C[C@@]3(OC)C2C=C(C)C3=O)C4C(C)(C)[C@]14OC(C)=O

InChI key

VCWNAJUHTLWQQT-XCHBPHIQSA-N

storage temp.

−20°C

Quality Level

100

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Biochem/physiol Actions

Weak phorbol ester agonist; very weak inflammatory and tumor promoting agent.

pictograms

Skull and crossbones
GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - Eye Irrit. 2 - Skin Irrit. 2

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
MKCR0292
MKCR5114
MKCR4074
MKBV7170V
MKBS9808V

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For patients with chronic lung diseases, such as chronic obstructive pulmonary disease (COPD), exacerbations are life-threatening events causing acute respiratory distress that can even lead to hospitalization and death. Although a great deal of effort has been put into research
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Pathogenic mycobacteria are able to persist intracellularly in macrophages, whereas non-pathogenic mycobacteria are effectively combated and eliminated after their phagocytosis. It is known that TGF-β plays an important role in this context. Infection with pathogenic mycobacteria such as Mycobacterium tuberculosis
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