P4038
Polycytidylic acid-Polyguanylic acid sodium salt
别名:
Poly(C) • Poly(G)
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关于此项目
form
solid
storage temp.
−20°C
InChI
1S/C10H14N5O8P.C9H14N3O8P/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(23-9)1-22-24(19,20)21;10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18/h2-3,5-6,9,16-17H,1H2,(H2,19,20,21)(H3,11,13,14,18);1-2,4,6-8,13-14H,3H2,(H2,10,11,15)(H2,16,17,18)/t3-,5-,6-,9-;4-,6-,7-,8-/m11/s1
InChI key
SDYIDXSXVMJNAE-FBGCOTALSA-N
Application
Polycytidylic acid-Polyguanylic acid (polyGC), a synthetic polynucleotide, is a double stranded homodimer used for physicochemical analysis of RNA structure.
Other Notes
Double-stranded homopolymer
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Marta Airoldi et al.
Journal of biomolecular structure & dynamics, 24(6), 561-570 (2007-05-19)
PolyGC was titrated with a strong base in the presence of increasing concentrations of NaCl (from 0.00 to 0.60M) either in water solution or with the polynucleotide solubilized in the aqueous core of reverse micelles, i.e., the cationic quaternary water-in-oil
Hole mobility in DNA: effects of static and dynamic structural fluctuations.
Ferdinand C Grozema et al.
Chemphyschem : a European journal of chemical physics and physical chemistry, 3(6), 536-539 (2002-12-06)
Javier Robalino et al.
Journal of virology, 78(19), 10442-10448 (2004-09-16)
Vertebrates mount a strong innate immune response against viruses, largely by activating the interferon system. Double-stranded RNA (dsRNA), a common intermediate formed during the life cycle of many viruses, is a potent trigger of this response. In contrast, no general
Susanna Cogoi et al.
Cancer gene therapy, 11(7), 465-476 (2004-05-01)
The Ki-ras gene is frequently mutated and/or overexpressed in human cancer. Since it is suspected to play a key role in the pathogenesis of many tumors, there is interest to search for strategies aiming at the specific inhibition of this
Ai-Min Guo et al.
Physical review. E, Statistical, nonlinear, and soft matter physics, 78(6 Pt 1), 061922-061922 (2009-03-05)
We report a theoretical study highlighting the fundamental effects of backbone disorder which simulates the environmental complications on charge transport properties of biological and synthetic DNA molecules. Based on effective tight-binding models of duplex DNA, the Lyapunov coefficient and current-voltage
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