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P4668

吡喹酮

Name: 吡喹酮
Brand: SIGMA

anthelminic, neurogenic

别名:

2-(环己基羰基)-1,2,3,6,7-11b-六氢-4H-吡嗪并-[2,1-a]-异喹啉-4-酮

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关于此项目

经验公式（希尔记法）:

C₁₉H₂₄N₂O₂

化学文摘社编号:

55268-74-1

分子量:

312.41

UNSPSC Code:

51452701

NACRES:

NA.85

PubChem Substance ID:

24278635

EC Number:

259-559-6

Beilstein/REAXYS Number:

761557

MDL number:

MFCD00058531

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属性

form

powder or crystals

antibiotic activity spectrum

parasites

mode of action

cell membrane | interferes

storage temp.

−20°C

SMILES string

O=C1CN(CC2N1CCc3ccccc23)C(=O)C4CCCCC4

InChI

1S/C19H24N2O2/c22-18-13-20(19(23)15-7-2-1-3-8-15)12-17-16-9-5-4-6-14(16)10-11-21(17)18/h4-6,9,15,17H,1-3,7-8,10-13H2

InChI key

FSVJFNAIGNNGKK-UHFFFAOYSA-N

说明

Application

吡喹酮是一种强效驱虫剂，可用于对抗血吸虫和多种绦虫的侵扰。它用于研究电压门控Ca²⁺ 通道，是一种潜在的小分子神经源性药物.

Biochem/physiol Actions

吡喹酮会增加被盖层对 Ca²⁺的渗透性，从而诱发的肌肉收缩和死亡。吡喹酮会导致血吸虫被盖层空泡的形成和分解。它对成年蠕虫比对幼年成年更有效。它会抑制葡萄糖吸收，从而降低糖水平，刺激乳酸释放。吡喹酮是一种强效驱虫剂，可用于对抗寄生扁虫（吸虫和绦虫）。最近的研究表明，吡喹酮能够与电压门控Ca²⁺通道亚基的变体以及肌动蛋白（某些 Ca²⁺通道的组分）结合。

Other Notes

保存于密闭容器内，置于干燥通风处。

1g,5g,25g

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hcodes

H412

pcodes

P273 - P501

Hazard Classifications

Aquatic Chronic 3

存储类别

11 - Combustible Solids

wgk

WGK 1

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

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全球贸易项目编号

货号	GTIN
P4668-5G	04061834375050
P4668-1G	04061834375036
P4668-25G	04061834375043